Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine
Nanoporous silica was applied in controlled releasing experiments. Different physical properties of the nanoporous silica, related to variations of the silica sources, affected the releasing behaviour. Two different silica precursors in nanoporous silica synthesis were investigated, tetraethoxysilan...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Prince of Songkla University
2009-11-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | http://www.rdoapp.psu.ac.th/html/sjst/journal/31-5/0125-3395-31-5-511-515.pdf |
| _version_ | 1818035785080766464 |
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| author | Chanatip Samart Chatchawan Sookman |
| author_facet | Chanatip Samart Chatchawan Sookman |
| author_sort | Chanatip Samart |
| collection | DOAJ |
| description | Nanoporous silica was applied in controlled releasing experiments. Different physical properties of the nanoporous silica, related to variations of the silica sources, affected the releasing behaviour. Two different silica precursors in nanoporous silica synthesis were investigated, tetraethoxysilane and sodium silicate. The nanoporous silica, which was obtained by tetraethoxysilane, gave the highest surface area (800 m2/g) and pore volume (1.2 cc/g). On the other hand, the nanoporous silica obtaining from sodium silicate showed the largest pore size (9 nm). The nanoporous silica with larger pore volume can load a higher amount of indigo carmine, which resulted in a fast release due to the large driving force between the silicaparticle and media solution. However, the releasing rate was not only affected by the pore volume, but also by the interactionbetween the silanol groups on the silica surface and molecules of indigo carmine. |
| first_indexed | 2024-12-10T07:00:34Z |
| format | Article |
| id | doaj.art-b9a63d79d7754b46b7a58d1650dfdb2e |
| institution | Directory Open Access Journal |
| issn | 0125-3395 |
| language | English |
| last_indexed | 2024-12-10T07:00:34Z |
| publishDate | 2009-11-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Songklanakarin Journal of Science and Technology (SJST) |
| spelling | doaj.art-b9a63d79d7754b46b7a58d1650dfdb2e2022-12-22T01:58:20ZengPrince of Songkla UniversitySongklanakarin Journal of Science and Technology (SJST)0125-33952009-11-01315511515Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmineChanatip SamartChatchawan SookmanNanoporous silica was applied in controlled releasing experiments. Different physical properties of the nanoporous silica, related to variations of the silica sources, affected the releasing behaviour. Two different silica precursors in nanoporous silica synthesis were investigated, tetraethoxysilane and sodium silicate. The nanoporous silica, which was obtained by tetraethoxysilane, gave the highest surface area (800 m2/g) and pore volume (1.2 cc/g). On the other hand, the nanoporous silica obtaining from sodium silicate showed the largest pore size (9 nm). The nanoporous silica with larger pore volume can load a higher amount of indigo carmine, which resulted in a fast release due to the large driving force between the silicaparticle and media solution. However, the releasing rate was not only affected by the pore volume, but also by the interactionbetween the silanol groups on the silica surface and molecules of indigo carmine.http://www.rdoapp.psu.ac.th/html/sjst/journal/31-5/0125-3395-31-5-511-515.pdfnanoporous silicacontrol releasedrug delivery |
| spellingShingle | Chanatip Samart Chatchawan Sookman Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine Songklanakarin Journal of Science and Technology (SJST) nanoporous silica control release drug delivery |
| title | Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine |
| title_full | Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine |
| title_fullStr | Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine |
| title_full_unstemmed | Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine |
| title_short | Effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine |
| title_sort | effect of silica sources in nanoporous silica synthesis on releasing behavior of indigo carmine |
| topic | nanoporous silica control release drug delivery |
| url | http://www.rdoapp.psu.ac.th/html/sjst/journal/31-5/0125-3395-31-5-511-515.pdf |
| work_keys_str_mv | AT chanatipsamart effectofsilicasourcesinnanoporoussilicasynthesisonreleasingbehaviorofindigocarmine AT chatchawansookman effectofsilicasourcesinnanoporoussilicasynthesisonreleasingbehaviorofindigocarmine |