The alleviating effect of Scutellaria amoena extract on the regulation of gut microbiota and its metabolites in NASH rats by inhibiting the NLRP3/ASC/caspase-1 axis

The alleviating effect of Scutellaria amoena extract on the regulation of gut microbiota and its metabolites in NASH rats by inhibiting the NLRP3/ASC/caspase-1 axis

Background:Scutellaria amoena (SA) is the root of S. amoena C.H. Wright of Labiatae, also known as Scutellaria southwestern. This is mainly distributed in Sichuan, Yunnan, and Guizhou in China. In southwest China, SA is used as an alternative method to genuine medicine for the treatment of allergy,...

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Main Authors: Yu-Ping Lin, Qiong-Lian Fang, Sheng-Nan Fu, Xin-Ping Li, Rui Shi, Cheng-Hong Du, Xue Qiao, Xun-Qing Yin, Yong-Cheng Zeng, Xiu-Juan Zhao, Yan Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
Scutellaria amoena
NASH
NLRP3/ASC/caspase-1 axis
gut microbiota
metabolites
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1143785/full

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