Mapping the Pax6 3’ untranslated region microRNA regulatory landscape

Mapping the Pax6 3’ untranslated region microRNA regulatory landscape

Abstract Background PAX6 is a homeodomain transcription factor that acts in a highly dosage-sensitive manner to regulate the development and function of the eyes, nose, central nervous system, gut, and endocrine pancreas. Several individual microRNAs (miRNA) have been implicated in regulating PAX6 i...

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Bibliographic Details
Main Authors: Bridget C. Ryan, Kieran Lowe, Laura Hanson, Talveen Gil, Lauren Braun, Perry L. Howard, Robert L. Chow
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Genomics
Subjects:
Gene regulation
Pax6
microRNA
Bioinformatics
Expression profiling
Pull-down assays
Online Access:http://link.springer.com/article/10.1186/s12864-018-5212-x

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