ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.

ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.

Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors, the P2Y(1) and P2Y(12) purinoceptors. Recently, we demonstrated that P2Y(1) and P2Y(12) purinoceptor activities are rapidly and reversibly modulated in human pla...

Full description

Bibliographic Details
Main Authors: Venkateswarlu Kanamarlapudi, Sian E Owens, Keya Saha, Robert J Pope, Stuart J Mundell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3420901?pdf=render

Similar Items

Similar Items