Tumor microenvironment in treatment of glioma

Glioma is one of the most malignant and fatal tumors in adults. Researchers and physicians endeavor to improve clinical efficacy towards it but made little achievement. In recent years, people have made advances in understanding characteristics and functions of tumor microenvironment and its role in...

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Bibliographic Details
Main Authors: Li Guijie, Qin Zhigang, Chen Zhuo, Xie Lijuan, Wang Ren, Zhao Hang
Format: Article
Language:English
Published: De Gruyter 2017-08-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2017-0035
Description
Summary:Glioma is one of the most malignant and fatal tumors in adults. Researchers and physicians endeavor to improve clinical efficacy towards it but made little achievement. In recent years, people have made advances in understanding characteristics and functions of tumor microenvironment and its role in different processes of tumor. In this paper, we describe the effects of tumor microenvironment on glioma proliferation, invasion and treatments. By explaining underlying mechanisms and enumerating new therapy strategies employing tumor microenvironment, we aim to provide novel ideas to improve clinical outcomes of glioma.
ISSN:2391-5463