Tumor microenvironment in treatment of glioma

Glioma is one of the most malignant and fatal tumors in adults. Researchers and physicians endeavor to improve clinical efficacy towards it but made little achievement. In recent years, people have made advances in understanding characteristics and functions of tumor microenvironment and its role in...

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Main Authors: Li Guijie, Qin Zhigang, Chen Zhuo, Xie Lijuan, Wang Ren, Zhao Hang
Format: Article
Language:English
Published: De Gruyter 2017-08-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2017-0035
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author Li Guijie
Qin Zhigang
Chen Zhuo
Xie Lijuan
Wang Ren
Zhao Hang
author_facet Li Guijie
Qin Zhigang
Chen Zhuo
Xie Lijuan
Wang Ren
Zhao Hang
author_sort Li Guijie
collection DOAJ
description Glioma is one of the most malignant and fatal tumors in adults. Researchers and physicians endeavor to improve clinical efficacy towards it but made little achievement. In recent years, people have made advances in understanding characteristics and functions of tumor microenvironment and its role in different processes of tumor. In this paper, we describe the effects of tumor microenvironment on glioma proliferation, invasion and treatments. By explaining underlying mechanisms and enumerating new therapy strategies employing tumor microenvironment, we aim to provide novel ideas to improve clinical outcomes of glioma.
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spelling doaj.art-b9afbbc911d34b288e6157f059c883ff2022-12-21T18:38:19ZengDe GruyterOpen Medicine2391-54632017-08-0112124725110.1515/med-2017-0035med-2017-0035Tumor microenvironment in treatment of gliomaLi Guijie0Qin Zhigang1Chen Zhuo2Xie Lijuan3Wang Ren4Zhao Hang5Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Union hospital of Jilin University, Changchun130033, ChinaDepartment of Neurosurgery, China-Japan Union hospital of Jilin University, Changchun130033,ChinaDepartment of Neurosurgery, China-Japan Union hospital of Jilin University, Changchun130033,ChinaDepartment of Vascular Surgery, China-Japan Union hospital of Jilin University, Changchun130033, ChinaDepartment of Neurosurgery, The People’s Hospital of Fusong County of Jilin Province, Fusong134500, ChinaDepartment of Neurosurgery, China-Japan Union hospital of Jilin University, Changchun130033,ChinaGlioma is one of the most malignant and fatal tumors in adults. Researchers and physicians endeavor to improve clinical efficacy towards it but made little achievement. In recent years, people have made advances in understanding characteristics and functions of tumor microenvironment and its role in different processes of tumor. In this paper, we describe the effects of tumor microenvironment on glioma proliferation, invasion and treatments. By explaining underlying mechanisms and enumerating new therapy strategies employing tumor microenvironment, we aim to provide novel ideas to improve clinical outcomes of glioma.https://doi.org/10.1515/med-2017-0035gliomatumor microenvironmenttreatment
spellingShingle Li Guijie
Qin Zhigang
Chen Zhuo
Xie Lijuan
Wang Ren
Zhao Hang
Tumor microenvironment in treatment of glioma
Open Medicine
glioma
tumor microenvironment
treatment
title Tumor microenvironment in treatment of glioma
title_full Tumor microenvironment in treatment of glioma
title_fullStr Tumor microenvironment in treatment of glioma
title_full_unstemmed Tumor microenvironment in treatment of glioma
title_short Tumor microenvironment in treatment of glioma
title_sort tumor microenvironment in treatment of glioma
topic glioma
tumor microenvironment
treatment
url https://doi.org/10.1515/med-2017-0035
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AT qinzhigang tumormicroenvironmentintreatmentofglioma
AT chenzhuo tumormicroenvironmentintreatmentofglioma
AT xielijuan tumormicroenvironmentintreatmentofglioma
AT wangren tumormicroenvironmentintreatmentofglioma
AT zhaohang tumormicroenvironmentintreatmentofglioma