IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review

IgG4-related or IgG4-associated hypophysitis is a rare disease characterized by the infiltration of IgG4-positive plasma cells into pituitary gland tissue. Gangliocytomas in the sellar region are also extremely rare and are associated with pituitary adenomas in the majority of cases. Sellar mucosa-a...

Full description

Bibliographic Details
Main Authors: Dongbo Zou, Li Jiang, Tao Yang, Jingmin Cheng, Yuan Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1253821/full
_version_ 1797629759917654016
author Dongbo Zou
Li Jiang
Tao Yang
Jingmin Cheng
Yuan Ma
author_facet Dongbo Zou
Li Jiang
Tao Yang
Jingmin Cheng
Yuan Ma
author_sort Dongbo Zou
collection DOAJ
description IgG4-related or IgG4-associated hypophysitis is a rare disease characterized by the infiltration of IgG4-positive plasma cells into pituitary gland tissue. Gangliocytomas in the sellar region are also extremely rare and are associated with pituitary adenomas in the majority of cases. Sellar mucosa-associated lymphoid tissue (MALT) lymphoma is an exceedingly rare condition. In this study, we present a case of IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma. However, to elucidate the potential pathophysiological relationship, it is imperative to gather additional cases of IgG4-related hypophysitis accompanied by MALT lymphoma and gangliocytoma.
first_indexed 2024-03-11T10:57:34Z
format Article
id doaj.art-b9aff45665764188812f11d2ac765e77
institution Directory Open Access Journal
issn 1664-2295
language English
last_indexed 2024-03-11T10:57:34Z
publishDate 2023-11-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Neurology
spelling doaj.art-b9aff45665764188812f11d2ac765e772023-11-13T04:26:34ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-11-011410.3389/fneur.2023.12538211253821IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature reviewDongbo Zou0Li Jiang1Tao Yang2Jingmin Cheng3Yuan Ma4Department of Neurosurgery, General Hospital of Western Theater Command, Chengdu, ChinaDepartment of Rheumatology and Immunology, The Second People's Hospital of Chengdu, Chengdu, ChinaDepartment of Neurosurgery, General Hospital of Western Theater Command, Chengdu, ChinaDepartment of Neurosurgery, General Hospital of Western Theater Command, Chengdu, ChinaDepartment of Neurosurgery, General Hospital of Western Theater Command, Chengdu, ChinaIgG4-related or IgG4-associated hypophysitis is a rare disease characterized by the infiltration of IgG4-positive plasma cells into pituitary gland tissue. Gangliocytomas in the sellar region are also extremely rare and are associated with pituitary adenomas in the majority of cases. Sellar mucosa-associated lymphoid tissue (MALT) lymphoma is an exceedingly rare condition. In this study, we present a case of IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma. However, to elucidate the potential pathophysiological relationship, it is imperative to gather additional cases of IgG4-related hypophysitis accompanied by MALT lymphoma and gangliocytoma.https://www.frontiersin.org/articles/10.3389/fneur.2023.1253821/fullIgG4-related hypophysitisMALT lymphomagangliocytomassellar regionheadachesvision loss
spellingShingle Dongbo Zou
Li Jiang
Tao Yang
Jingmin Cheng
Yuan Ma
IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review
Frontiers in Neurology
IgG4-related hypophysitis
MALT lymphoma
gangliocytomas
sellar region
headaches
vision loss
title IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review
title_full IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review
title_fullStr IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review
title_full_unstemmed IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review
title_short IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review
title_sort igg4 associated hypophysitis coexisting with malt lymphoma and gangliocytoma first case report and literature review
topic IgG4-related hypophysitis
MALT lymphoma
gangliocytomas
sellar region
headaches
vision loss
url https://www.frontiersin.org/articles/10.3389/fneur.2023.1253821/full
work_keys_str_mv AT dongbozou igg4associatedhypophysitiscoexistingwithmaltlymphomaandgangliocytomafirstcasereportandliteraturereview
AT lijiang igg4associatedhypophysitiscoexistingwithmaltlymphomaandgangliocytomafirstcasereportandliteraturereview
AT taoyang igg4associatedhypophysitiscoexistingwithmaltlymphomaandgangliocytomafirstcasereportandliteraturereview
AT jingmincheng igg4associatedhypophysitiscoexistingwithmaltlymphomaandgangliocytomafirstcasereportandliteraturereview
AT yuanma igg4associatedhypophysitiscoexistingwithmaltlymphomaandgangliocytomafirstcasereportandliteraturereview