OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats

OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats

Abstract Objective Ovarian tumour domain deubiquitinase with linear linkage specificity (OTULIN) is a potent negative regulator of the nuclear factor-κB (NF-κB) signalling pathway, and it plays a strong neuroprotective role following acute ischemic stroke. Electroacupuncture (EA) is an effective adj...

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Bibliographic Details
Main Authors: Hongbei Xu, You Wang, Yong Luo
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Molecular Medicine
Subjects:
Acute ischaemic stroke
Electroacupuncture
OTULIN
NF-κB signalling pathway
Brain injury
Glial activation
Online Access:https://doi.org/10.1186/s10020-021-00297-0

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