Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients
IntroductionPsoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients’ quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and physicians use the Disease Activity Index for Psoria...
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| Format: | Article |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1332432/full |
| _version_ | 1797353905087053824 |
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| author | Marika Lo Monaco Marika Lo Monaco Raffaella Mallaci Bocchio Giuseppe Natoli Annarita Giardina Ignazio Cangemi Salvatore Scibetta Christiano Argano Salvatore Corrao Salvatore Corrao |
| author_facet | Marika Lo Monaco Marika Lo Monaco Raffaella Mallaci Bocchio Giuseppe Natoli Annarita Giardina Ignazio Cangemi Salvatore Scibetta Christiano Argano Salvatore Corrao Salvatore Corrao |
| author_sort | Marika Lo Monaco |
| collection | DOAJ |
| description | IntroductionPsoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients’ quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and physicians use the Disease Activity Index for Psoriatic Arthritis (DAPSA) to evaluate disease activity in PsA. The study aimed to assess the relationship between PROMs and the DAPSA score in consecutive outpatients affected by PsA.Materials and methodsA cross-sectional study was conducted from March 2018 to October 2020 at the PsA clinic of the ARNAS Civico in Palermo (Italy), enrolling outpatients with PsA. Patients were assessed for their disease activity according to the DAPSA score, and PROMs, such as PHQ-9, HAQ, FACIT-F, and PsAID, were evaluated. Linear regression analysis evaluated the relationship between the DAPSA Score and the included PROMs.Results158 PsA consecutive peripheral subset psoriatic arthritis outpatients were recruited. The median years of illness was 10.6 (9.3–11.9), and the median DAPSA score was 19.02 (9–33.1). The regression analysis highlighted a strong relationship between the DAPSA score and the PsAID (adjR2 26%, p < 0.0001), the FACIT-F (adjR2 25.4%, p < 0.0001), the HAQ (adjR2 23.7%, p < 0.0001), and PHQ-9 (adjR2 15%, p < 0.0001).ConclusionPROMs are strongly associated with the DAPSA score, but it allows in-depth evaluation of the impact of the disease on different domains of PsA patients’ life. |
| first_indexed | 2024-03-08T13:37:40Z |
| format | Article |
| id | doaj.art-b9bcc6f005b343e9bf9e71fed53027c8 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-08T13:37:40Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-b9bcc6f005b343e9bf9e71fed53027c82024-01-16T15:03:07ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-01-011010.3389/fmed.2023.13324321332432Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patientsMarika Lo Monaco0Marika Lo Monaco1Raffaella Mallaci Bocchio2Giuseppe Natoli3Annarita Giardina4Ignazio Cangemi5Salvatore Scibetta6Christiano Argano7Salvatore Corrao8Salvatore Corrao9Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties [PROMISE], University of Palermo, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyDepartment of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties [PROMISE], University of Palermo, Palermo, ItalyDepartment of Clinical Medicine, Internal Medicine Unit with Rheumatology, Dermatology, Diabetology and Tertiary Diabetic Foot Healthcare, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, ItalyIntroductionPsoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients’ quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and physicians use the Disease Activity Index for Psoriatic Arthritis (DAPSA) to evaluate disease activity in PsA. The study aimed to assess the relationship between PROMs and the DAPSA score in consecutive outpatients affected by PsA.Materials and methodsA cross-sectional study was conducted from March 2018 to October 2020 at the PsA clinic of the ARNAS Civico in Palermo (Italy), enrolling outpatients with PsA. Patients were assessed for their disease activity according to the DAPSA score, and PROMs, such as PHQ-9, HAQ, FACIT-F, and PsAID, were evaluated. Linear regression analysis evaluated the relationship between the DAPSA Score and the included PROMs.Results158 PsA consecutive peripheral subset psoriatic arthritis outpatients were recruited. The median years of illness was 10.6 (9.3–11.9), and the median DAPSA score was 19.02 (9–33.1). The regression analysis highlighted a strong relationship between the DAPSA score and the PsAID (adjR2 26%, p < 0.0001), the FACIT-F (adjR2 25.4%, p < 0.0001), the HAQ (adjR2 23.7%, p < 0.0001), and PHQ-9 (adjR2 15%, p < 0.0001).ConclusionPROMs are strongly associated with the DAPSA score, but it allows in-depth evaluation of the impact of the disease on different domains of PsA patients’ life.https://www.frontiersin.org/articles/10.3389/fmed.2023.1332432/fullpatient reported outcomesnurse assessmentnursingpsoriatic diseasedisease activityquality of life |
| spellingShingle | Marika Lo Monaco Marika Lo Monaco Raffaella Mallaci Bocchio Giuseppe Natoli Annarita Giardina Ignazio Cangemi Salvatore Scibetta Christiano Argano Salvatore Corrao Salvatore Corrao Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients Frontiers in Medicine patient reported outcomes nurse assessment nursing psoriatic disease disease activity quality of life |
| title | Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients |
| title_full | Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients |
| title_fullStr | Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients |
| title_full_unstemmed | Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients |
| title_short | Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients |
| title_sort | critical importance of patient reported outcomes for a comprehensive assessment of psoriatic arthritis patients |
| topic | patient reported outcomes nurse assessment nursing psoriatic disease disease activity quality of life |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1332432/full |
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