Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population
(1) Background: Insertion-deletion (InDel) markers show the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) and are considered alternative markers in forensic genetics. (2) Methods: Allelic frequencies and corresponding forensic efficiency parameters of 30 a...
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MDPI AG
2022-09-01
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| Series: | Genes |
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| Online Access: | https://www.mdpi.com/2073-4425/13/10/1683 |
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| author | Monica Abreu-Glowacka Witold Pepinski Eliza Michalak Magdalena Konarzewska Krzysztof Zak Malgorzata Skawronska Anna Niemcunowicz-Janica Ireneusz Soltyszewski Pawel Krajewski Czeslaw Zaba |
| author_facet | Monica Abreu-Glowacka Witold Pepinski Eliza Michalak Magdalena Konarzewska Krzysztof Zak Malgorzata Skawronska Anna Niemcunowicz-Janica Ireneusz Soltyszewski Pawel Krajewski Czeslaw Zaba |
| author_sort | Monica Abreu-Glowacka |
| collection | DOAJ |
| description | (1) Background: Insertion-deletion (InDel) markers show the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) and are considered alternative markers in forensic genetics. (2) Methods: Allelic frequencies and corresponding forensic efficiency parameters of 30 autosomal polymorphic InDel loci included in the Investigator DIPplex kit (Qiagen) were obtained in a sample of 631 unrelated Polish individuals. Allelic frequency data were compared with those reported for selected populations (3) Results: All the loci conformed with Hardy-Weinberg equilibrium after applying a Bonferroni correction and no pair-wise significant linkage disequilibrium was detected. (4) Conclusions: DIPplex Kit differences were high among populations worldwide. The InDel markers are highly discriminating for human identification purposes in the Polish population. |
| first_indexed | 2024-03-09T20:11:56Z |
| format | Article |
| id | doaj.art-b9c1824c5a0d4fbea7ce73ace4796c92 |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-09T20:11:56Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-b9c1824c5a0d4fbea7ce73ace4796c922023-11-24T00:14:20ZengMDPI AGGenes2073-44252022-09-011310168310.3390/genes13101683Population Genetic Data of 30 Insertion-Deletion Markers in the Polish PopulationMonica Abreu-Glowacka0Witold Pepinski1Eliza Michalak2Magdalena Konarzewska3Krzysztof Zak4Malgorzata Skawronska5Anna Niemcunowicz-Janica6Ireneusz Soltyszewski7Pawel Krajewski8Czeslaw Zaba9Department of Forensic Medicine, Poznan University of Medical Sciences, 60-781 Poznan, PolandDepartment of Forensic Medicine, Medical University of Bialystok, 15-269 Bialystok, PolandDepartment of Forensic Medicine, Poznan University of Medical Sciences, 60-781 Poznan, PolandDepartment of Forensic Medicine, Medical University of Warsaw, 02-007 Warsaw, PolandDepartment of Forensic Medicine, Medical University of Warsaw, 02-007 Warsaw, PolandDepartment of Forensic Medicine, Medical University of Bialystok, 15-269 Bialystok, PolandDepartment of Forensic Medicine, Medical University of Bialystok, 15-269 Bialystok, PolandDepartment of Forensic Medicine, Medical University of Warsaw, 02-007 Warsaw, PolandDepartment of Forensic Medicine, Medical University of Warsaw, 02-007 Warsaw, PolandDepartment of Forensic Medicine, Poznan University of Medical Sciences, 60-781 Poznan, Poland(1) Background: Insertion-deletion (InDel) markers show the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) and are considered alternative markers in forensic genetics. (2) Methods: Allelic frequencies and corresponding forensic efficiency parameters of 30 autosomal polymorphic InDel loci included in the Investigator DIPplex kit (Qiagen) were obtained in a sample of 631 unrelated Polish individuals. Allelic frequency data were compared with those reported for selected populations (3) Results: All the loci conformed with Hardy-Weinberg equilibrium after applying a Bonferroni correction and no pair-wise significant linkage disequilibrium was detected. (4) Conclusions: DIPplex Kit differences were high among populations worldwide. The InDel markers are highly discriminating for human identification purposes in the Polish population.https://www.mdpi.com/2073-4425/13/10/1683PolandpopulationInDelsInvestigator DIPplexforensic genetics |
| spellingShingle | Monica Abreu-Glowacka Witold Pepinski Eliza Michalak Magdalena Konarzewska Krzysztof Zak Malgorzata Skawronska Anna Niemcunowicz-Janica Ireneusz Soltyszewski Pawel Krajewski Czeslaw Zaba Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population Genes Poland population InDels Investigator DIPplex forensic genetics |
| title | Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population |
| title_full | Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population |
| title_fullStr | Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population |
| title_full_unstemmed | Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population |
| title_short | Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population |
| title_sort | population genetic data of 30 insertion deletion markers in the polish population |
| topic | Poland population InDels Investigator DIPplex forensic genetics |
| url | https://www.mdpi.com/2073-4425/13/10/1683 |
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