Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex.

Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex.

RATIONALE: Integrin-linked kinase (ILK) has been proposed as a novel molecular target that has translational potential in diverse cardiac diseases, since its upregulation promotes a broadly cardioprotective phenotype. However, ILK has been implicated as both a cardioprotective and oncogenic target,...

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Bibliographic Details
Main Authors: Alexandra Traister, Mark Walsh, Shabana Aafaqi, Mingliang Lu, Xiaojing Dai, Mark R Henkleman, Abdul Momen, Yu-Quing Zhou, Mansoor Husain, Sara Arab, Sara Piran, Gregory Hannigan, John G Coles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832499?pdf=render

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