HPV detection in oral carcinomas
The authors set out in this study to verify the presence of low- and high-risk DNA of human papillomavirus (HPV) in oral cancer by means of the hybrid capture Digene® test (São Paulo-SP, Brazil) in smears from exfoliative cytology and also to compare the findings with those of conventional light mic...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Patologia Clínica
2004-02-01
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| Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000100007&tlng=en |
| _version_ | 1818979164245458944 |
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| author | Aurora Karla de Lacerda Vidal Arnaldo de França Caldas Júnior Roberto José Vieira de Mello Virgínia Ribes A. Brandão Getúlio Isidoro da Rocha Eliane Taromaru |
| author_facet | Aurora Karla de Lacerda Vidal Arnaldo de França Caldas Júnior Roberto José Vieira de Mello Virgínia Ribes A. Brandão Getúlio Isidoro da Rocha Eliane Taromaru |
| author_sort | Aurora Karla de Lacerda Vidal |
| collection | DOAJ |
| description | The authors set out in this study to verify the presence of low- and high-risk DNA of human papillomavirus (HPV) in oral cancer by means of the hybrid capture Digene® test (São Paulo-SP, Brazil) in smears from exfoliative cytology and also to compare the findings with those of conventional light microscopy (hematoxylin-eosin (HE)/Papanicolaou). Forty individuals gave their written informed consent to participate in the study and also had their clinical data analyzed. The 40 exfoliative cytology examinations performed to date produced the following results: 29 (72.5%) negative for low- and high-risk HPV-DNA; nine (22.5%) positive for low- and high-risk HPV-DNA; one (2.5%) positive for low-risk HPV-DNA; and one (2.5%) positive for high-risk HPV-DNA. There was agreement among the findings for the presence of DNA-HPV for both exfoliative cytology (smear to hybrid capture Digene® test and the cytological smear readings made by conventional light microscopy). It was therefore concluded that the HPV virus may be a cocarcinogen of the mouth cancer as it is in the cervix cancer. |
| first_indexed | 2024-12-20T16:55:11Z |
| format | Article |
| id | doaj.art-b9d1e8d5dcec427aaa54313cc1e7757b |
| institution | Directory Open Access Journal |
| issn | 1678-4774 |
| language | English |
| last_indexed | 2024-12-20T16:55:11Z |
| publishDate | 2004-02-01 |
| publisher | Sociedade Brasileira de Patologia Clínica |
| record_format | Article |
| series | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| spelling | doaj.art-b9d1e8d5dcec427aaa54313cc1e7757b2022-12-21T19:32:45ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1678-47742004-02-01401212610.1590/S1676-24442004000100007HPV detection in oral carcinomasAurora Karla de Lacerda Vidal0Arnaldo de França Caldas Júnior1Roberto José Vieira de Mello2Virgínia Ribes A. Brandão3Getúlio Isidoro da Rocha4Eliane Taromaru5Universidade de PernambucoUniversidade de PernambucoUniversidade Federal de PernambucoUniversidade de PernambucoHospital de Câncer de PernambucoLaboratório Digene do BrasilThe authors set out in this study to verify the presence of low- and high-risk DNA of human papillomavirus (HPV) in oral cancer by means of the hybrid capture Digene® test (São Paulo-SP, Brazil) in smears from exfoliative cytology and also to compare the findings with those of conventional light microscopy (hematoxylin-eosin (HE)/Papanicolaou). Forty individuals gave their written informed consent to participate in the study and also had their clinical data analyzed. The 40 exfoliative cytology examinations performed to date produced the following results: 29 (72.5%) negative for low- and high-risk HPV-DNA; nine (22.5%) positive for low- and high-risk HPV-DNA; one (2.5%) positive for low-risk HPV-DNA; and one (2.5%) positive for high-risk HPV-DNA. There was agreement among the findings for the presence of DNA-HPV for both exfoliative cytology (smear to hybrid capture Digene® test and the cytological smear readings made by conventional light microscopy). It was therefore concluded that the HPV virus may be a cocarcinogen of the mouth cancer as it is in the cervix cancer.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000100007&tlng=enOral cancerHPVExfoliative cytologyHybrid capture |
| spellingShingle | Aurora Karla de Lacerda Vidal Arnaldo de França Caldas Júnior Roberto José Vieira de Mello Virgínia Ribes A. Brandão Getúlio Isidoro da Rocha Eliane Taromaru HPV detection in oral carcinomas Jornal Brasileiro de Patologia e Medicina Laboratorial Oral cancer HPV Exfoliative cytology Hybrid capture |
| title | HPV detection in oral carcinomas |
| title_full | HPV detection in oral carcinomas |
| title_fullStr | HPV detection in oral carcinomas |
| title_full_unstemmed | HPV detection in oral carcinomas |
| title_short | HPV detection in oral carcinomas |
| title_sort | hpv detection in oral carcinomas |
| topic | Oral cancer HPV Exfoliative cytology Hybrid capture |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000100007&tlng=en |
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