Approach to Orofacial Granulomatosis and Review of Literature
Background and Aim : Orofacial granulomatosis (OFG) comprises a group of diseases characterized by non-caseating granulomatous inflammation affecting the soft tissues of the oral and maxillofacial region. Wiesenfeld introduced the term orofacial granulomatosis in 1985 for the first time. The prec...
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| Format: | Article |
| Language: | English |
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Islamic Dental Association of Iran
2012-07-01
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| Series: | Journal of Islamic Dental Association of Iran |
| Subjects: | |
| Online Access: | http://jidai.ir/browse.php?a_code=A-10-1-618&slc_lang=en&sid=1 |
| _version_ | 1819034466644918272 |
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| author | Abbas Javadzade Ates sa Pakfetrat Farnaz Falaki Amir Seyyedi |
| author_facet | Abbas Javadzade Ates sa Pakfetrat Farnaz Falaki Amir Seyyedi |
| author_sort | Abbas Javadzade |
| collection | DOAJ |
| description | Background and Aim : Orofacial granulomatosis (OFG) comprises a group of diseases characterized by non-caseating granulomatous inflammation affecting the soft tissues of the oral and maxillofacial region.
Wiesenfeld introduced the term orofacial granulomatosis in 1985 for the first time. The precise cause of OFG is unknown however, some theories have been suggested including allergy, infection and genetic predisposition.
The clinical presentation can be highly variable, making the diagnosis difficult to establish.
The aim of this review was to define clinical features, differential diagnosis and treatment protocols of OFG .
Materials and Methods : All English articles from 1950 to 2010 in Pubmed, InterScience, ScienceDirect, Google Scholar databases were searched using the keywords : orofacial granulomatosis, approach, and treatment. Persian articles were also selected from Iran Medex .
Results and Conclusion : Because of the relatively nonspecific clinical findings associated with a variety of granulomatous diseases, the diagnosis of orofacial granulomatous often presents a dilemma for the clinician. The most common differential diagnosis includes Crohn's disease, sarcoidosis, and infection. However, a variety of other conditions may be associated with granuloma formation. Often an extensive clinical, microscopic, and laboratory evaluation may be required to reach to definite diagnosis and proper treatment . |
| first_indexed | 2024-12-21T07:34:11Z |
| format | Article |
| id | doaj.art-b9d5719788be479c9edc56b627f0c76a |
| institution | Directory Open Access Journal |
| issn | 2383-3041 2383-3041 |
| language | English |
| last_indexed | 2024-12-21T07:34:11Z |
| publishDate | 2012-07-01 |
| publisher | Islamic Dental Association of Iran |
| record_format | Article |
| series | Journal of Islamic Dental Association of Iran |
| spelling | doaj.art-b9d5719788be479c9edc56b627f0c76a2022-12-21T19:11:30ZengIslamic Dental Association of IranJournal of Islamic Dental Association of Iran2383-30412383-30412012-07-01243111121Approach to Orofacial Granulomatosis and Review of LiteratureAbbas Javadzade0Ates sa Pakfetrat1Farnaz Falaki2Amir Seyyedi3 Associate Professor, Department of Oral Medicine, School of Dentistry, Mashhad University of Medical Sciences. Mashhad, Iran Associate Professor, Department of Oral Medicine, School of Dentistry, Mashhad University of Medical Sciences. Mashhad, Iran Assistant Professor, Department of Oral Medicine, School of Dentistry, Mashhad University of Medical Sciences. Mashhad, Iran Assistant Professor, Department of Oral Medicine, School of Dentistry, Urmia University of Medical Sciences. Urmia, Iran Background and Aim : Orofacial granulomatosis (OFG) comprises a group of diseases characterized by non-caseating granulomatous inflammation affecting the soft tissues of the oral and maxillofacial region. Wiesenfeld introduced the term orofacial granulomatosis in 1985 for the first time. The precise cause of OFG is unknown however, some theories have been suggested including allergy, infection and genetic predisposition. The clinical presentation can be highly variable, making the diagnosis difficult to establish. The aim of this review was to define clinical features, differential diagnosis and treatment protocols of OFG . Materials and Methods : All English articles from 1950 to 2010 in Pubmed, InterScience, ScienceDirect, Google Scholar databases were searched using the keywords : orofacial granulomatosis, approach, and treatment. Persian articles were also selected from Iran Medex . Results and Conclusion : Because of the relatively nonspecific clinical findings associated with a variety of granulomatous diseases, the diagnosis of orofacial granulomatous often presents a dilemma for the clinician. The most common differential diagnosis includes Crohn's disease, sarcoidosis, and infection. However, a variety of other conditions may be associated with granuloma formation. Often an extensive clinical, microscopic, and laboratory evaluation may be required to reach to definite diagnosis and proper treatment .http://jidai.ir/browse.php?a_code=A-10-1-618&slc_lang=en&sid=1Orofacial granulomatosisApproachTreatment |
| spellingShingle | Abbas Javadzade Ates sa Pakfetrat Farnaz Falaki Amir Seyyedi Approach to Orofacial Granulomatosis and Review of Literature Journal of Islamic Dental Association of Iran Orofacial granulomatosis Approach Treatment |
| title | Approach to Orofacial Granulomatosis and Review of Literature |
| title_full | Approach to Orofacial Granulomatosis and Review of Literature |
| title_fullStr | Approach to Orofacial Granulomatosis and Review of Literature |
| title_full_unstemmed | Approach to Orofacial Granulomatosis and Review of Literature |
| title_short | Approach to Orofacial Granulomatosis and Review of Literature |
| title_sort | approach to orofacial granulomatosis and review of literature |
| topic | Orofacial granulomatosis Approach Treatment |
| url | http://jidai.ir/browse.php?a_code=A-10-1-618&slc_lang=en&sid=1 |
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