Influence of Angiopoietin Treatment with Hypoxia and Normoxia on Human Intervertebral Disc Progenitor Cell’s Proliferation, Metabolic Activity, and Phenotype
Increasing evidence implicates intervertebral disc (IVD) degeneration as a major contributor to low back pain. In addition to a series of pathogenic processes, degenerated IVDs become vascularized in contrast to healthy IVDs. In this context, angiopoietin (Ang) plays a crucial role and is involved i...
Main Authors: | Muriel C. Bischof, Sonja Häckel, Andrea Oberli, Andreas S. Croft, Katharina A. C. Oswald, Christoph E. Albers, Benjamin Gantenbein, Julien Guerrero |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Applied Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3417/11/15/7144 |
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