Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method
<abstract language="eng">The dissolution enthalpy (ΔH0soln) of sodium sulfacetamide in water was determined by means of isoperibolic solution calorimetry. It was found that ΔH0soln diminishes as the drug concentration increases. Otherwise, the calorimetric values ob...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
2008-01-01
|
| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000600033 |
| _version_ | 1819292679887912960 |
|---|---|
| author | Daniel R. Torres Alejandro Sosnik Diego Chiappetta Edgar F. Vargas Fleming Martínez |
| author_facet | Daniel R. Torres Alejandro Sosnik Diego Chiappetta Edgar F. Vargas Fleming Martínez |
| author_sort | Daniel R. Torres |
| collection | DOAJ |
| description | <abstract language="eng">The dissolution enthalpy (ΔH0soln) of sodium sulfacetamide in water was determined by means of isoperibolic solution calorimetry. It was found that ΔH0soln diminishes as the drug concentration increases. Otherwise, the calorimetric values obtained as a function of the drug concentration were significantly different than those predicted by the van't Hoff method. It was demonstrated that the later is not a fully reliable method for the determination of ΔH0soln values in the specific case of highly soluble sodium salts. The observed phenomenon could be explained by the presence of strong solute-solute interactions at high salt concentrations, in addition to solute-solvent and solvent-solvent interactions. |
| first_indexed | 2024-12-24T03:58:22Z |
| format | Article |
| id | doaj.art-b9d903202d9f43a3a6cb7296b17ca42c |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-24T03:58:22Z |
| publishDate | 2008-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-b9d903202d9f43a3a6cb7296b17ca42c2022-12-21T17:16:23ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642008-01-013161455145910.1590/S0100-40422008000600033Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff methodDaniel R. TorresAlejandro SosnikDiego ChiappettaEdgar F. VargasFleming Martínez<abstract language="eng">The dissolution enthalpy (ΔH0soln) of sodium sulfacetamide in water was determined by means of isoperibolic solution calorimetry. It was found that ΔH0soln diminishes as the drug concentration increases. Otherwise, the calorimetric values obtained as a function of the drug concentration were significantly different than those predicted by the van't Hoff method. It was demonstrated that the later is not a fully reliable method for the determination of ΔH0soln values in the specific case of highly soluble sodium salts. The observed phenomenon could be explained by the presence of strong solute-solute interactions at high salt concentrations, in addition to solute-solvent and solvent-solvent interactions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000600033sodium sulfacetamidesolution calorimetryvan't Hoff method |
| spellingShingle | Daniel R. Torres Alejandro Sosnik Diego Chiappetta Edgar F. Vargas Fleming Martínez Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method Química Nova sodium sulfacetamide solution calorimetry van't Hoff method |
| title | Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method |
| title_full | Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method |
| title_fullStr | Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method |
| title_full_unstemmed | Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method |
| title_short | Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff Dissolution enthalpy of sodium sulfacetamide in water: comparison between solution isoperibolic calorimetry and the van't Hoff method |
| title_sort | entalpia de disolucion de sulfacetamida sodica en agua comparacion entre la calorimetria isoperibolica de solucion y el metodo de van t hoff dissolution enthalpy of sodium sulfacetamide in water comparison between solution isoperibolic calorimetry and the van t hoff method |
| topic | sodium sulfacetamide solution calorimetry van't Hoff method |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000600033 |
| work_keys_str_mv | AT danielrtorres entalpiadedisoluciondesulfacetamidasodicaenaguacomparacionentrelacalorimetriaisoperibolicadesolucionyelmetododevanthoffdissolutionenthalpyofsodiumsulfacetamideinwatercomparisonbetweensolutionisoperiboliccalorimetryandthevanthoffmethod AT alejandrososnik entalpiadedisoluciondesulfacetamidasodicaenaguacomparacionentrelacalorimetriaisoperibolicadesolucionyelmetododevanthoffdissolutionenthalpyofsodiumsulfacetamideinwatercomparisonbetweensolutionisoperiboliccalorimetryandthevanthoffmethod AT diegochiappetta entalpiadedisoluciondesulfacetamidasodicaenaguacomparacionentrelacalorimetriaisoperibolicadesolucionyelmetododevanthoffdissolutionenthalpyofsodiumsulfacetamideinwatercomparisonbetweensolutionisoperiboliccalorimetryandthevanthoffmethod AT edgarfvargas entalpiadedisoluciondesulfacetamidasodicaenaguacomparacionentrelacalorimetriaisoperibolicadesolucionyelmetododevanthoffdissolutionenthalpyofsodiumsulfacetamideinwatercomparisonbetweensolutionisoperiboliccalorimetryandthevanthoffmethod AT flemingmartinez entalpiadedisoluciondesulfacetamidasodicaenaguacomparacionentrelacalorimetriaisoperibolicadesolucionyelmetododevanthoffdissolutionenthalpyofsodiumsulfacetamideinwatercomparisonbetweensolutionisoperiboliccalorimetryandthevanthoffmethod |