Serum Metabonomic Study of Patients With Acute Coronary Syndrome Using Ultra-Performance Liquid Chromatography Orbitrap Mass Spectrometer

Serum Metabonomic Study of Patients With Acute Coronary Syndrome Using Ultra-Performance Liquid Chromatography Orbitrap Mass Spectrometer

Acute coronary syndrome (ACS) can cause arrhythmia, heart failure, and even sudden death. Our aim in this study was to identify potential metabolic biomarkers in patients with ACS. The serum metabonomics approach based on ultra-performance liquid chromatography (UPLC)/Orbitrap mass spectrometer (MS)...

Full description

Bibliographic Details
Main Authors:	Lei Song, Zhongxiao Zhang, Zhaohui Qiu, Tingbo Jiang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-02-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	acute coronary syndrome metabonomic serum biomarkers UPLC-Orbitrap/MS
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2021.637621/full

Similar Items

Metabonomic study of the protective effect of Fukeqianjin formula on multi-pathogen induced pelvic inflammatory disease in rats
by: Yan Zhang, et al.
Published: (2018-12-01)

The Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Pinostrobin in Rats: Ultra-High-Performance Liquid Chromatography Coupled With Linear Trap Quadrupole Orbitrap Mass Spectrometry Studies
by: Xiaoya Sun, et al.
Published: (2020-11-01)

Metabolite Differences of Polyphenols in Different Litchi Cultivars (<i>Litchi chinensis</i> Sonn.) Based on Extensive Targeted Metabonomics
by: Nonghui Jiang, et al.
Published: (2021-02-01)

Pharmacokinetics and Metabolite Profiling of Trepibutone in Rats Using Ultra-High Performance Liquid Chromatography Combined With Hybrid Quadrupole-Orbitrap and Triple Quadrupole Mass Spectrometers
by: Zhi Sun, et al.
Published: (2019-11-01)

Sixty mycotoxins in nuts and dried fruits simultaneously detected by QuEChERS combined with UPLC-Orbitrap/MS
by: WANG Wei, et al.
Published: (2022-07-01)

Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics
by: Wuhuan Lu, et al.
Published: (2021-09-01)

Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
by: Ning Ma, et al.
Published: (2017-12-01)

Analysis of Chemical Constituents in Wuzi-Yanzong-Wan by UPLC-ESI-LTQ-Orbitrap-MS
by: Dixin Zou, et al.
Published: (2015-12-01)

Characterization of Fumonisin A-Series by High-Resolution Liquid Chromatography-Orbitrap Mass Spectrometry
by: Masayoshi Tamura, et al.
Published: (2014-08-01)

Identification of phytochemicals from Lentinus edodes and Auricularia auricula with UPLC-Q-Exactive Orbitrap MS
by: Lili Cui, et al.
Published: (2022-09-01)

Chemical Profile Determination and Quantitative Analysis of Components in Oryeong-san Using UHPLC-Q-Orbitrap-MS and UPLC-TQ-MS/MS
by: Seol Jang, et al.
Published: (2023-04-01)

Rapid Characterizaiton of Chemical Constituents of the Tubers of <i>Gymnadenia conopsea</i> by UPLC–Orbitrap–MS/MS Analysis
by: Xin Wang, et al.
Published: (2020-02-01)

Detection and characterization of the metabolites of rutaecarpine in rats based on ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer
by: Wei Cai, et al.
Published: (2017-01-01)

Comparison of the Polyphenolic Profile of <i>Medicago sativa L</i>. and <i>Trifolium pratense L</i>. Sprouts in Different Germination Stages Using the UHPLC-Q Exactive Hybrid Quadrupole Orbitrap High-Resolution Mass Spectrometry
by: Elena Roxana Chiriac, et al.
Published: (2020-05-01)

Determination of Lekethromycin, a Novel Macrolide Lactone, in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study
by: Hongzhi Xiao, et al.
Published: (2020-10-01)

Evaluation of Lipidomics Profile of Quinoa Flour and Changes during Storage Based on Ultra Performance Liquid Chromatography Coupled with Quadrupole Exactive Orbitrap Mass Spectrometry
by: Ya-bo Ba, et al.
Published: (2023-12-01)

Discrimination for geographical origin of Panax quinquefolius L. using UPLC Q‐Orbitrap MS‐based metabolomics approach
by: Shifeng Pang, et al.
Published: (2023-08-01)

Identification of Metabolites of Turmeric Extract in Rats by UPLC-Q-Extractive Orbitrap MS
by: WANG Yuan1, et al.
Published: (2022-03-01)

Simultaneous Qualitation and Quantitation of Chlorogenic Acids in Kuding Tea Using Ultra-High-Performance Liquid Chromatography–Diode Array Detection Coupled with Linear Ion Trap–Orbitrap Mass Spectrometer
by: Yanyun Che, et al.
Published: (2016-12-01)

Identification and Quantitative Characterization of PSORI-CM01, a Chinese Medicine Formula for Psoriasis Therapy, by Liquid Chromatography Coupled with an LTQ Orbitrap Mass Spectrometer
by: Shao-Dan Chen, et al.
Published: (2015-01-01)

Qualitative Profiling and Quantitative Analysis of Major Constituents in Jinmu-tang by UHPLC-Q-Orbitrap-MS and UPLC-TQ-MS/MS
by: Seol Jang, et al.
Published: (2022-11-01)

The Application of Ultra-High-Performance Liquid Chromatography Coupled with a LTQ-Orbitrap Mass Technique to Reveal the Dynamic Accumulation of Secondary Metabolites in Licorice under ABA Stress
by: Da Li, et al.
Published: (2017-10-01)

Chemical Variations among Shengmaisan-Based TCM Patent Drugs by Ultra-High Performance Liquid Chromatography Coupled with Hybrid Quadrupole Orbitrap Mass Spectrometry
by: Lulu Xu, et al.
Published: (2021-06-01)

The Response of Volvariella volvacea to Low-Temperature Stress Based on Metabonomics
by: Xu Zhao, et al.
Published: (2020-07-01)

Screening 89 Pesticides in Fishery Drugs by Ultrahigh Performance Liquid Chromatography Tandem Quadrupole-Orbitrap Mass Spectrometer
by: Shou-Ying Wang, et al.
Published: (2019-09-01)

Environmental fate of cefquinome: Adsorption and degradation
by: Jicheng Qiu, et al.
Published: (2022-10-01)

Untargeted metabolomic approach to study the serum metabolites in women with polycystic ovary syndrome
by: Ying Yu, et al.
Published: (2021-08-01)

Identification and Quantification of Fumonisin A1, A2, and A3 in Corn by High-Resolution Liquid Chromatography-Orbitrap Mass Spectrometry
by: Masayoshi Tamura, et al.
Published: (2015-02-01)

A GC-MS Based Metabonomics Study of Rheumatoid Arthritis and the Interventional Effects of the Simiaowan in Rats
by: Yuming Wang, et al.
Published: (2015-12-01)

Metabolomics study of flavonoids in Coreopsis tinctoria of different origins by UPLC–MS/MS
by: Yi Wang, et al.
Published: (2022-12-01)

Uncertainty Evaluation for Determination of 6 Sildenafil Derivatives in Oral Liquid by UPLC-Q/Orbitrap HRMS
by: Shenping ZHANG, et al.
Published: (2023-06-01)

Metabolic Variation Dictates Cardiac Pathogenesis in Patients With Tetralogy of Fallot
by: Jianyang Liu, et al.
Published: (2022-01-01)

Intestinal microbial 16S sequencing and LC-MS metabonomic analysis revealed differences between young and old cats
by: Tongguan Tian, et al.
Published: (2023-06-01)

The Metabolites and Mechanism Analysis of Genistin against Hyperlipidemia via the UHPLC-Q-Exactive Orbitrap Mass Spectrometer and Metabolomics
by: Zhe Li, et al.
Published: (2023-02-01)

A Comparative Study of Serum Pharmacochemistry of Kai-Xin-San in Normal and AD Rats Using UPLC-LTQ-Orbitrap-MS
by: Lin Yang, et al.
Published: (2022-12-01)

Detection of Type A Trichothecene Di-Glucosides Produced in Corn by High-Resolution Liquid Chromatography-Orbitrap Mass Spectrometry
by: Hitoshi Nagashima, et al.
Published: (2013-03-01)

Standards-Based UPLC-Q-Exactive Orbitrap MS Systematically Identifies 36 Bioactive Compounds in <i>Ampelopsis grossedentata</i> (Vine Tea)
by: Rongxin Cai, et al.
Published: (2022-10-01)

Phytochemical analysis, UPLC-ESI-Orbitrap-MS analysis, biological activity, and toxicity of extracts from Tripleurospermum limosum (Maxim.) Pobed
by: Meihua Chen, et al.
Published: (2022-05-01)

Application of Ultra-High-Performance Liquid Chromatography Coupled with LTQ-Orbitrap Mass Spectrometry for the Qualitative and Quantitative Analysis of Polygonum multiflorum Thumb. and Its Processed Products
by: Teng-Hua Wang, et al.
Published: (2015-12-01)

An Exploration of Dynamic Changes in the Mulberry Growth Process Based on UPLC-Q-Orbitrap-MS, HS-SPME-GC-MS, and HS-GC-IMS
by: Shufang Wu, et al.
Published: (2023-09-01)