The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia

The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia

Animal studies indicate that hypothalamic dysfunction plays a major role in type 2 diabetes mellitus (T2DM) development, and that insulin resistance and inflammation are important mechanisms involved in this disorder. However, it remains unclear how T2DM and antidiabetic treatments affect the human...

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Bibliographic Details
Main Authors: Martin J.T. Kalsbeek, Samantha E.C. Wolff, Nikita L. Korpel, Susanne E. la Fleur, Johannes A. Romijn, Eric Fliers, Andries Kalsbeek, Dick F. Swaab, Inge Huitinga, Elly M. Hol, Chun-Xia Yi
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-08-01
Series:JCI Insight
Subjects:
Endocrinology
Neuroscience
Online Access:https://doi.org/10.1172/jci.insight.133868

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