Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University

Individuals with history of blood transfusion, transplantation or pregnancy might develop alloantibodies specific to red blood cell antigens. This work aimed to screen and identify alloantibodies in blood samples from the Community Medical Service Project, Faculty of Associated Medical Sciences, Chi...

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Main Authors: Pattaraporn Chanungklang, Preeyanat Vongchan
Format: Article
Language:English
Published: Chaing Mai University 2012-05-01
Series:Journal of Associated Medical Sciences
Online Access:https://www.tci-thaijo.org/index.php/bulletinAMS/article/view/60035
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author Pattaraporn Chanungklang
Preeyanat Vongchan
author_facet Pattaraporn Chanungklang
Preeyanat Vongchan
author_sort Pattaraporn Chanungklang
collection DOAJ
description Individuals with history of blood transfusion, transplantation or pregnancy might develop alloantibodies specific to red blood cell antigens. This work aimed to screen and identify alloantibodies in blood samples from the Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University. Antibody detection was performed in 1,048 blood samples from 5 community sites during April-December 2011. The result showed that distribution of blood group O, B, A, and AB were 459 (43.8%), 306 (29.2%), 228 (21.8%), and 55 (5.2%), respectively. Four individuals were Rh negative (0.38%). There were 41 blood samples (3.9%) showed positive with antibody screening but only 13 cases (3 male and 10 female, 31.7%) were identified according to small volume of blood sample. Identified alloantibodies included anti-Mia (8 samples, 61.5%), anti-P1 (2 samples, 15.4%), anti-M (2 samples, 15.4%), and anti-D (1 sample, 7.7%). The additional data, including history of blood transfusion and/or pregnancy were reviewed. History of blood transfusion and/or pregnancy in women was reviewed and it was corresponded to those alloantibodies reported. One sample of anti-M was detected from male subject who showed no history of blood transfusion. Results from this finding provide enefit for preparing of appropriate blood components for those with alloantibodies in order to reduce risk of blood transfusion reaction.
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spelling doaj.art-b9e3608e70e643128d4713b02ca5983e2022-12-21T20:13:31ZengChaing Mai UniversityJournal of Associated Medical Sciences2539-60562539-60562012-05-01452303060035Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai UniversityPattaraporn Chanungklang0Preeyanat Vongchan1Division of Transfusion Science, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai UniversityDivision of Transfusion Science, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai UniversityIndividuals with history of blood transfusion, transplantation or pregnancy might develop alloantibodies specific to red blood cell antigens. This work aimed to screen and identify alloantibodies in blood samples from the Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University. Antibody detection was performed in 1,048 blood samples from 5 community sites during April-December 2011. The result showed that distribution of blood group O, B, A, and AB were 459 (43.8%), 306 (29.2%), 228 (21.8%), and 55 (5.2%), respectively. Four individuals were Rh negative (0.38%). There were 41 blood samples (3.9%) showed positive with antibody screening but only 13 cases (3 male and 10 female, 31.7%) were identified according to small volume of blood sample. Identified alloantibodies included anti-Mia (8 samples, 61.5%), anti-P1 (2 samples, 15.4%), anti-M (2 samples, 15.4%), and anti-D (1 sample, 7.7%). The additional data, including history of blood transfusion and/or pregnancy were reviewed. History of blood transfusion and/or pregnancy in women was reviewed and it was corresponded to those alloantibodies reported. One sample of anti-M was detected from male subject who showed no history of blood transfusion. Results from this finding provide enefit for preparing of appropriate blood components for those with alloantibodies in order to reduce risk of blood transfusion reaction.https://www.tci-thaijo.org/index.php/bulletinAMS/article/view/60035
spellingShingle Pattaraporn Chanungklang
Preeyanat Vongchan
Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University
Journal of Associated Medical Sciences
title Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University
title_full Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University
title_fullStr Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University
title_full_unstemmed Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University
title_short Screening and identication of alloantibodies in blood samples from Community Medical Service Project, Faculty of Associated Medical Sciences, Chiang Mai University
title_sort screening and identication of alloantibodies in blood samples from community medical service project faculty of associated medical sciences chiang mai university
url https://www.tci-thaijo.org/index.php/bulletinAMS/article/view/60035
work_keys_str_mv AT pattarapornchanungklang screeningandidenticationofalloantibodiesinbloodsamplesfromcommunitymedicalserviceprojectfacultyofassociatedmedicalscienceschiangmaiuniversity
AT preeyanatvongchan screeningandidenticationofalloantibodiesinbloodsamplesfromcommunitymedicalserviceprojectfacultyofassociatedmedicalscienceschiangmaiuniversity