Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats
Objective: Worldwide, phytotherapy methods acquire great importance, and studies in this field are increasing their importance each day. This study, it was aimed to examine total antioxidant, oxidant status, oxidative DNA damage, glucose and hemoglobin A1c levels and the effects of barley grass juic...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hitit University
2023-10-01
|
| Series: | Hitit Medical Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/3076043 |
| _version_ | 1797221442016772096 |
|---|---|
| author | Bahat Comba Yıldıray Basbugan Devrim Sarıpınar Aksu Leyla Mis Arzu Comba |
| author_facet | Bahat Comba Yıldıray Basbugan Devrim Sarıpınar Aksu Leyla Mis Arzu Comba |
| author_sort | Bahat Comba |
| collection | DOAJ |
| description | Objective: Worldwide, phytotherapy methods acquire great importance, and studies in this field are increasing their importance each day. This study, it was aimed to examine total antioxidant, oxidant status, oxidative DNA damage, glucose and hemoglobin A1c levels and the effects of barley grass juice on these parameters in rats with diabetes mellitus.
Material and Method: Four groups were formed for the study and 6 male rats weighing 250-350 g were used in each group. Control Group; physiological saline was injected via intraperitoneal., Diabetic Group; created using streptozotocin, Barley Grass Group; Barley grass juice (3 ml/rat/day) was given orally for 4 weeks, Diabetic and Barley Grass Group; was injected streptozotocin and barley grass juice was given by oral for 4 weeks.
Results: It was determined that barley grass juice decreased blood sugar, glucose, hemoglobin A1c, total oxidative status and oxidative stress index values, increased total anti-oxidative status value, and body weights in streptozotocin-induced diabetes. In addition, it was determined that the addition of barley grass juice provided a significant protective effect and improvement in these parameters.
Conclusion: Based on these findings, we can say that barley grass juice has an antidiabetic-antioxidant effect and weight gain in diabetes mellitus |
| first_indexed | 2024-03-11T15:44:24Z |
| format | Article |
| id | doaj.art-b9e47ca7f6054e9f90c1ce427cf47406 |
| institution | Directory Open Access Journal |
| issn | 2687-4717 |
| language | English |
| last_indexed | 2024-04-24T13:05:30Z |
| publishDate | 2023-10-01 |
| publisher | Hitit University |
| record_format | Article |
| series | Hitit Medical Journal |
| spelling | doaj.art-b9e47ca7f6054e9f90c1ce427cf474062024-04-05T08:04:17ZengHitit UniversityHitit Medical Journal2687-47172023-10-015314915510.52827/hititmedj.1281145150Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic RatsBahat Comba0Yıldıray Basbugan1Devrim Sarıpınar Aksu2Leyla Mis3Arzu Comba4HİTİT ÜNİVERSİTESİYÜZÜNCÜ YIL ÜNİVERSİTESİYÜZÜNCÜ YIL ÜNİVERSİTESİYÜZÜNCÜ YIL ÜNİVERSİTESİHİTİT ÜNİVERSİTESİObjective: Worldwide, phytotherapy methods acquire great importance, and studies in this field are increasing their importance each day. This study, it was aimed to examine total antioxidant, oxidant status, oxidative DNA damage, glucose and hemoglobin A1c levels and the effects of barley grass juice on these parameters in rats with diabetes mellitus. Material and Method: Four groups were formed for the study and 6 male rats weighing 250-350 g were used in each group. Control Group; physiological saline was injected via intraperitoneal., Diabetic Group; created using streptozotocin, Barley Grass Group; Barley grass juice (3 ml/rat/day) was given orally for 4 weeks, Diabetic and Barley Grass Group; was injected streptozotocin and barley grass juice was given by oral for 4 weeks. Results: It was determined that barley grass juice decreased blood sugar, glucose, hemoglobin A1c, total oxidative status and oxidative stress index values, increased total anti-oxidative status value, and body weights in streptozotocin-induced diabetes. In addition, it was determined that the addition of barley grass juice provided a significant protective effect and improvement in these parameters. Conclusion: Based on these findings, we can say that barley grass juice has an antidiabetic-antioxidant effect and weight gain in diabetes mellitushttps://dergipark.org.tr/tr/download/article-file/3076043barley grassdiabetes mellitusglucosehba1ctas-tosdna damagearpa çimidiabetglukozhba1ctas-tosdna hasarı |
| spellingShingle | Bahat Comba Yıldıray Basbugan Devrim Sarıpınar Aksu Leyla Mis Arzu Comba Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats Hitit Medical Journal barley grass diabetes mellitus glucose hba1c tas-tos dna damage arpa çimi diabet glukoz hba1c tas-tos dna hasarı |
| title | Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats |
| title_full | Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats |
| title_fullStr | Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats |
| title_full_unstemmed | Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats |
| title_short | Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats |
| title_sort | effect of barley grass on antioxidant capacity and dna damage in diabetic rats |
| topic | barley grass diabetes mellitus glucose hba1c tas-tos dna damage arpa çimi diabet glukoz hba1c tas-tos dna hasarı |
| url | https://dergipark.org.tr/tr/download/article-file/3076043 |
| work_keys_str_mv | AT bahatcomba effectofbarleygrassonantioxidantcapacityanddnadamageindiabeticrats AT yıldıraybasbugan effectofbarleygrassonantioxidantcapacityanddnadamageindiabeticrats AT devrimsarıpınaraksu effectofbarleygrassonantioxidantcapacityanddnadamageindiabeticrats AT leylamis effectofbarleygrassonantioxidantcapacityanddnadamageindiabeticrats AT arzucomba effectofbarleygrassonantioxidantcapacityanddnadamageindiabeticrats |