Oral Delivery of mRNA Vaccine by Plant-Derived Extracellular Vesicle Carriers

Oral Delivery of mRNA Vaccine by Plant-Derived Extracellular Vesicle Carriers

mRNA-based vaccines were effective in contrasting SARS-CoV-2 infection. However, they presented several limitations of storage and supply chain, and their parenteral administration elicited a limited mucosal IgA immune response. Extracellular vesicles (EVs) have been recognized as a mechanism of cel...

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Bibliographic Details
Main Authors: Margherita A. C. Pomatto, Chiara Gai, Federica Negro, Lucia Massari, Maria Chiara Deregibus, Francesco Giuseppe De Rosa, Giovanni Camussi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
oral
capsule
extracellular vesicles
plant
delivery
carrier
Online Access:https://www.mdpi.com/2073-4409/12/14/1826

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