Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study
Abstract Features of the gut microbiota have been associated with several chronic diseases and longevity in preclinical models as well as in observational studies. Whether these relations underlie causal effects in humans remains to be established. We aimed to determine whether the gut microbiota in...
Main Authors: | Eloi Gagnon, Patricia L. Mitchell, Hasanga D. Manikpurage, Erik Abner, Nele Taba, Tõnu Esko, Nooshin Ghodsian, Sébastien Thériault, Patrick Mathieu, Benoit J. Arsenault |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
|
Series: | Journal of Translational Medicine |
Online Access: | https://doi.org/10.1186/s12967-022-03799-5 |
Similar Items
-
Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases
by: Eloi Gagnon, et al.
Published: (2022-10-01) -
Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease
by: Émilie Gobeil, et al.
Published: (2022-05-01) -
Blood Levels of the <i>SMOC1</i> Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study
by: Nooshin Ghodsian, et al.
Published: (2021-11-01) -
Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease
by: Nooshin Ghodsian, et al.
Published: (2021-11-01) -
Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms
by: Samuel Mathieu, et al.
Published: (2022-09-01)