Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli
Hydroxycinnamic acids (HCAs) are phenolic compounds produced by the secondary metabolism of edible plants and are the most abundant phenolic acids in our diet. The antimicrobial capacity of HCAs is an important function attributed to these phenolic acids in the defense of plants against microbiologi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/12/6/1294 |
| _version_ | 1797596337807556608 |
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| author | Félix López de Felipe |
| author_facet | Félix López de Felipe |
| author_sort | Félix López de Felipe |
| collection | DOAJ |
| description | Hydroxycinnamic acids (HCAs) are phenolic compounds produced by the secondary metabolism of edible plants and are the most abundant phenolic acids in our diet. The antimicrobial capacity of HCAs is an important function attributed to these phenolic acids in the defense of plants against microbiological threats, and bacteria have developed diverse mechanisms to counter the antimicrobial stress imposed by these compounds, including their metabolism into different microbial derivatives. The metabolism of HCAs has been intensively studied in <i>Lactobacillus</i> spp., as the metabolic transformation of HCAs by these bacteria contributes to the biological activity of these acids in plant and human habitats or to improve the nutritional quality of fermented foods. The main mechanisms known to date used by <i>Lactobacillus</i> spp. to metabolize HCAs are enzymatic decarboxylation and/or reduction. Here, recent advances in the knowledge regarding the enzymes that contribute to these two enzymatic conversions, the genes involved, their regulation and the physiological significance to lactobacilli are reviewed and critically discussed. |
| first_indexed | 2024-03-11T02:50:02Z |
| format | Article |
| id | doaj.art-b9e7cc09acca4750ae428e00c77f0958 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-11T02:50:02Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-b9e7cc09acca4750ae428e00c77f09582023-11-18T09:04:11ZengMDPI AGAntioxidants2076-39212023-06-01126129410.3390/antiox12061294Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in LactobacilliFélix López de Felipe0Laboratorio de Biotecnología Bacteriana, Instituto de Ciencia y Tecnología de los Alimentos y Nutrición (ICTAN), CSIC, José Antonio Novais 10, 28040 Madrid, SpainHydroxycinnamic acids (HCAs) are phenolic compounds produced by the secondary metabolism of edible plants and are the most abundant phenolic acids in our diet. The antimicrobial capacity of HCAs is an important function attributed to these phenolic acids in the defense of plants against microbiological threats, and bacteria have developed diverse mechanisms to counter the antimicrobial stress imposed by these compounds, including their metabolism into different microbial derivatives. The metabolism of HCAs has been intensively studied in <i>Lactobacillus</i> spp., as the metabolic transformation of HCAs by these bacteria contributes to the biological activity of these acids in plant and human habitats or to improve the nutritional quality of fermented foods. The main mechanisms known to date used by <i>Lactobacillus</i> spp. to metabolize HCAs are enzymatic decarboxylation and/or reduction. Here, recent advances in the knowledge regarding the enzymes that contribute to these two enzymatic conversions, the genes involved, their regulation and the physiological significance to lactobacilli are reviewed and critically discussed.https://www.mdpi.com/2076-3921/12/6/1294hydroxycinnamic acidsmetabolismmolecular bases<i>Lactobacillus</i> |
| spellingShingle | Félix López de Felipe Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli Antioxidants hydroxycinnamic acids metabolism molecular bases <i>Lactobacillus</i> |
| title | Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli |
| title_full | Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli |
| title_fullStr | Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli |
| title_full_unstemmed | Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli |
| title_short | Revised Aspects into the Molecular Bases of Hydroxycinnamic Acid Metabolism in Lactobacilli |
| title_sort | revised aspects into the molecular bases of hydroxycinnamic acid metabolism in lactobacilli |
| topic | hydroxycinnamic acids metabolism molecular bases <i>Lactobacillus</i> |
| url | https://www.mdpi.com/2076-3921/12/6/1294 |
| work_keys_str_mv | AT felixlopezdefelipe revisedaspectsintothemolecularbasesofhydroxycinnamicacidmetabolisminlactobacilli |