OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM
Presently, the expressed tendency to deterioration in parameters of semen is noted in the world, at the same time both the quantity of spermatozoa, and their functional properties decrease. The spermatogenesis is a difficult, extremely sensible process of cellular differentiation; the different syst...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2017-04-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/628 |
| _version_ | 1797237360598974464 |
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| author | E. A. Kirilenko V. F. Onopko |
| author_facet | E. A. Kirilenko V. F. Onopko |
| author_sort | E. A. Kirilenko |
| collection | DOAJ |
| description | Presently, the expressed tendency to deterioration in parameters of semen is noted in the world, at the same time both the quantity of spermatozoa, and their functional properties decrease. The spermatogenesis is a difficult, extremely sensible process of cellular differentiation; the different systems of organism participate in its adjusting. Violations in any links affect the process of spermatogenesis, and finally, affects parameters of semen. This systematic review of the literature analyses recent publications concerning studies of oxidative stress influencing male fertility. The oxidative stress - the very widespread version of pathology, which accompanies and/or is one of key mechanisms in development of many types of reproductive disorders in men. There are three main mechanisms of impaired fertile function of men in the development of oxidative stress: reducing sperm motility, violation of ability of spermatozoa to penetrate into oocyte and spermatozoa DNA damage. The factors promoting its development are numerous: environmental pollution, life style, addictions, stress, diabetes, and varicocele; however, the most frequent reason of development of oxidative stress in reproductive system of men are infectious and inflammatory diseases and antispermal autoimmune processes in a man's urogenital tract. Considering possible participation of free-radical processes in patospermia development, it is worthwhile to use antioxidants in all cases of the man's infertility connected with oxidative stress. |
| first_indexed | 2024-03-08T12:18:16Z |
| format | Article |
| id | doaj.art-b9e7d0867d244706952add2a20d88dc0 |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:18:31Z |
| publishDate | 2017-04-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-b9e7d0867d244706952add2a20d88dc02024-03-28T07:49:17ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962017-04-012210210810.12737/article_59a614fd84d146.40261567628OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEME. A. Kirilenko0V. F. Onopko1Irkutsk State Medical UniversityIrkutsk State Medical UniversityPresently, the expressed tendency to deterioration in parameters of semen is noted in the world, at the same time both the quantity of spermatozoa, and their functional properties decrease. The spermatogenesis is a difficult, extremely sensible process of cellular differentiation; the different systems of organism participate in its adjusting. Violations in any links affect the process of spermatogenesis, and finally, affects parameters of semen. This systematic review of the literature analyses recent publications concerning studies of oxidative stress influencing male fertility. The oxidative stress - the very widespread version of pathology, which accompanies and/or is one of key mechanisms in development of many types of reproductive disorders in men. There are three main mechanisms of impaired fertile function of men in the development of oxidative stress: reducing sperm motility, violation of ability of spermatozoa to penetrate into oocyte and spermatozoa DNA damage. The factors promoting its development are numerous: environmental pollution, life style, addictions, stress, diabetes, and varicocele; however, the most frequent reason of development of oxidative stress in reproductive system of men are infectious and inflammatory diseases and antispermal autoimmune processes in a man's urogenital tract. Considering possible participation of free-radical processes in patospermia development, it is worthwhile to use antioxidants in all cases of the man's infertility connected with oxidative stress.https://www.actabiomedica.ru/jour/article/view/628oxidative stressreactive oxygen speciesmale infertilityantioxidant |
| spellingShingle | E. A. Kirilenko V. F. Onopko OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM Acta Biomedica Scientifica oxidative stress reactive oxygen species male infertility antioxidant |
| title | OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM |
| title_full | OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM |
| title_fullStr | OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM |
| title_full_unstemmed | OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM |
| title_short | OXIDATIVE STRESS AND MALE FERTILITY: MODERN VIEW ON THE PROBLEM |
| title_sort | oxidative stress and male fertility modern view on the problem |
| topic | oxidative stress reactive oxygen species male infertility antioxidant |
| url | https://www.actabiomedica.ru/jour/article/view/628 |
| work_keys_str_mv | AT eakirilenko oxidativestressandmalefertilitymodernviewontheproblem AT vfonopko oxidativestressandmalefertilitymodernviewontheproblem |