Diterpenoids from the aerial parts of Isodon macrocalyx
To study the constituents of Isodon macrocalyx, thirteen diterpenoids were isolated and purified from the aerial parts of I. macrocalyx by means of various column chromatographic techniques, including silica gel, ODS, Sephadex LH-20 and RP-C18 pre-HPLC. The structures of the isolated diterpenoids we...
| Główni autorzy: | , , , , , , |
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| Format: | Artykuł |
| Język: | zho |
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China Science Publishing & Media Ltd. (CSPM)
2023-11-01
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| Seria: | Guangxi Zhiwu |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.11931/guihaia.gxzw202207002 |
| _version_ | 1827247979643273216 |
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| author | Yanling CHANG Xiaoqin LIANG Yan HUANG Liwei PAN Ping HOU Chenyang REN Jun LI |
| author_facet | Yanling CHANG Xiaoqin LIANG Yan HUANG Liwei PAN Ping HOU Chenyang REN Jun LI |
| author_sort | Yanling CHANG |
| collection | DOAJ |
| description | To study the constituents of Isodon macrocalyx, thirteen diterpenoids were isolated and purified from the aerial parts of I. macrocalyx by means of various column chromatographic techniques, including silica gel, ODS, Sephadex LH-20 and RP-C18 pre-HPLC. The structures of the isolated diterpenoids were determined on the basis of analyses of spectroscopic methods (1H NMR and 13C NMR spectroscopy), high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), and comparison of their spectroscopic data with previously reported data. The results showed that the diterpenoids were identified as 19-hydroxytotarol (1), macrophynin E (2), inumakoic acid (3), inumakiol D (4), 4β-carboxy-19-nortotarol (5), (-)-lambertic acid (6), 2-oxo-5-fagonene (7), isodoterniofiln B (8), longikaurin E (9), longikaurin A (10), rabdotemin H (11), 16S-dihydrolongikaurin A (12), and ent-3S,16S,17-trihydroxy-kauran-2-one (13). All diterpenoids were isolated from I. macrocalyx for the first time. |
| first_indexed | 2025-03-21T23:24:27Z |
| format | Article |
| id | doaj.art-b9e8accd19e44ac2a8d1e89c44b5f11b |
| institution | Directory Open Access Journal |
| issn | 1000-3142 |
| language | zho |
| last_indexed | 2025-03-21T23:24:27Z |
| publishDate | 2023-11-01 |
| publisher | China Science Publishing & Media Ltd. (CSPM) |
| record_format | Article |
| series | Guangxi Zhiwu |
| spelling | doaj.art-b9e8accd19e44ac2a8d1e89c44b5f11b2024-05-20T06:29:38ZzhoChina Science Publishing & Media Ltd. (CSPM)Guangxi Zhiwu1000-31422023-11-0143112113211910.11931/guihaia.gxzw2022070021000-3142(2023)11-2113-07Diterpenoids from the aerial parts of Isodon macrocalyxYanling CHANG0Xiaoqin LIANG1Yan HUANG2Liwei PAN3Ping HOU4Chenyang REN5Jun LI6State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, Guangxi, ChinaTo study the constituents of Isodon macrocalyx, thirteen diterpenoids were isolated and purified from the aerial parts of I. macrocalyx by means of various column chromatographic techniques, including silica gel, ODS, Sephadex LH-20 and RP-C18 pre-HPLC. The structures of the isolated diterpenoids were determined on the basis of analyses of spectroscopic methods (1H NMR and 13C NMR spectroscopy), high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), and comparison of their spectroscopic data with previously reported data. The results showed that the diterpenoids were identified as 19-hydroxytotarol (1), macrophynin E (2), inumakoic acid (3), inumakiol D (4), 4β-carboxy-19-nortotarol (5), (-)-lambertic acid (6), 2-oxo-5-fagonene (7), isodoterniofiln B (8), longikaurin E (9), longikaurin A (10), rabdotemin H (11), 16S-dihydrolongikaurin A (12), and ent-3S,16S,17-trihydroxy-kauran-2-one (13). All diterpenoids were isolated from I. macrocalyx for the first time.https://doi.org/10.11931/guihaia.gxzw202207002isodon macrocalyxditerpenoid19-hydroxytotarol16s-dihydrolongikaurin arabdotemin h |
| spellingShingle | Yanling CHANG Xiaoqin LIANG Yan HUANG Liwei PAN Ping HOU Chenyang REN Jun LI Diterpenoids from the aerial parts of Isodon macrocalyx Guangxi Zhiwu isodon macrocalyx diterpenoid 19-hydroxytotarol 16s-dihydrolongikaurin a rabdotemin h |
| title | Diterpenoids from the aerial parts of Isodon macrocalyx |
| title_full | Diterpenoids from the aerial parts of Isodon macrocalyx |
| title_fullStr | Diterpenoids from the aerial parts of Isodon macrocalyx |
| title_full_unstemmed | Diterpenoids from the aerial parts of Isodon macrocalyx |
| title_short | Diterpenoids from the aerial parts of Isodon macrocalyx |
| title_sort | diterpenoids from the aerial parts of isodon macrocalyx |
| topic | isodon macrocalyx diterpenoid 19-hydroxytotarol 16s-dihydrolongikaurin a rabdotemin h |
| url | https://doi.org/10.11931/guihaia.gxzw202207002 |
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