Specific immunosuppression with inducible Foxp3-transduced polyclonal T cells.

Specific immunosuppression with inducible Foxp3-transduced polyclonal T cells.

Forkhead box p3 (Foxp3)-expressing regulatory T cells are key mediators of peripheral tolerance suppressing undesirable immune responses. Ectopic expression of Foxp3 confers regulatory T cell phenotype to conventional T cells, lending itself to therapeutic use in the prevention of autoimmunity and t...

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Bibliographic Details
Main Authors:	Kristian G Andersen, Tracey Butcher, Alexander G Betz
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2008-11-01
Series:	PLoS Biology
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18998771/?tool=EBI

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