Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry
Abstract Background Numerous studies have reported clinical endpoints following coronary revascularization using bioresorbable vascular scaffolds (BVS), while information about the impact on health-related quality of life is sparse. In this analysis of the German-Austrian ABSORB RegIstRy, the 2 year...
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BMC
2022-08-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-022-02815-2 |
| _version_ | 1811340190087643136 |
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| author | Kathrin Pahmeier Silke Neusser Christian Hamm Johannes Kastner Jochen Wöhrle Ralf Zahn Stephan Achenbach Julinda Mehilli Tommaso Gori Christoph Naber Holger Nef Till Neumann Gert Richardt Axel Schmermund Christoph Claas Thomas Riemer Janine Biermann-Stallwitz For the GABI-R Study Group |
| author_facet | Kathrin Pahmeier Silke Neusser Christian Hamm Johannes Kastner Jochen Wöhrle Ralf Zahn Stephan Achenbach Julinda Mehilli Tommaso Gori Christoph Naber Holger Nef Till Neumann Gert Richardt Axel Schmermund Christoph Claas Thomas Riemer Janine Biermann-Stallwitz For the GABI-R Study Group |
| author_sort | Kathrin Pahmeier |
| collection | DOAJ |
| description | Abstract Background Numerous studies have reported clinical endpoints following coronary revascularization using bioresorbable vascular scaffolds (BVS), while information about the impact on health-related quality of life is sparse. In this analysis of the German-Austrian ABSORB RegIstRy, the 2 year results concerning quality of life development in a large cohort of patients treated with BVS were reported. Methods Data were collected at baseline as well as 30 days, 6 and 24 months after coronary revascularization using BVS. The EQ-5D score, EQ visual analogue scale (VAS) and Seattle Angina Questionnaire (SAQ) were determined for each time point. Patients were categorized according to the indication for coronary revascularization [acute coronary syndrome (ACS), stable angina pectoris (SAP), silent myocardial ischemia (SMI), or other]. Binary logistic regression analysis was performed to determine factors that predict above-average scores two years after implantation. Results Data from 1317 patients in 88 centres were included. Reasons for revascularization were: ACS (n = 643), SAP (n = 443), SMI (n = 52), and other (n = 179). Mean EQ-5D was significantly increased after six months, while a value comparable to baseline was found two years after implantation. EQ VAS and four of five dimensions of SAQ were significantly improved over baseline at all follow-up surveys. Particularly strong improvements were seen in SAQ scores angina frequency and quality of life. Binary regressions showed different statistically significant predictors in the respective models. Conclusions Following coronary revascularization with BVS strong decrease in self-reported angina frequency and increase of self-reported quality of life were observed with continuous improvements over two years of follow-up. Trial registration ClinicalTrials.gov Identifier: NCT02066623. |
| first_indexed | 2024-04-13T18:38:14Z |
| format | Article |
| id | doaj.art-b9f23122378f41e298da59b0ce38bcd8 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-04-13T18:38:14Z |
| publishDate | 2022-08-01 |
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| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-b9f23122378f41e298da59b0ce38bcd82022-12-22T02:34:49ZengBMCBMC Cardiovascular Disorders1471-22612022-08-012211810.1186/s12872-022-02815-2Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registryKathrin Pahmeier0Silke Neusser1Christian Hamm2Johannes Kastner3Jochen Wöhrle4Ralf Zahn5Stephan Achenbach6Julinda Mehilli7Tommaso Gori8Christoph Naber9Holger Nef10Till Neumann11Gert Richardt12Axel Schmermund13Christoph Claas14Thomas Riemer15Janine Biermann-Stallwitz16For the GABI-R Study GroupInstitute for Health Care Management and Research, University Duisburg-EssenInstitute for Health Care Management and Research, University Duisburg-EssenUniversity of GiessenDivision of Cardiology, Department of Medicine II, Medical University of ViennaDepartment of Cardiology, Medical Campus Lake ConstanceDepartment of Cardiology, Clinical Center of the City of LudwigshafenFriedrich-Alexander-Universität Erlangen-Nürnberg (FAU)Department of Internal Medicine I (Cardiology), Ludwig-Maximilians-University of MunichDepartment of Cardiology I, University Medical Center, Johannes Gutenberg University MainzDepartment of Internal Medicine I, Cardiology and Intensive Care, Klinikum WilhelmshavenUniversity of GiessenOutpatient Department CardiologyDepartment of Cardiology and Angiology, Segeberger Kliniken GmbHCardioangiologisches Centrum Bethanien, CCBIHF GmbH, Institut Für HerzinfarktforschungIHF GmbH, Institut Für HerzinfarktforschungInstitute for Health Care Management and Research, University Duisburg-EssenAbstract Background Numerous studies have reported clinical endpoints following coronary revascularization using bioresorbable vascular scaffolds (BVS), while information about the impact on health-related quality of life is sparse. In this analysis of the German-Austrian ABSORB RegIstRy, the 2 year results concerning quality of life development in a large cohort of patients treated with BVS were reported. Methods Data were collected at baseline as well as 30 days, 6 and 24 months after coronary revascularization using BVS. The EQ-5D score, EQ visual analogue scale (VAS) and Seattle Angina Questionnaire (SAQ) were determined for each time point. Patients were categorized according to the indication for coronary revascularization [acute coronary syndrome (ACS), stable angina pectoris (SAP), silent myocardial ischemia (SMI), or other]. Binary logistic regression analysis was performed to determine factors that predict above-average scores two years after implantation. Results Data from 1317 patients in 88 centres were included. Reasons for revascularization were: ACS (n = 643), SAP (n = 443), SMI (n = 52), and other (n = 179). Mean EQ-5D was significantly increased after six months, while a value comparable to baseline was found two years after implantation. EQ VAS and four of five dimensions of SAQ were significantly improved over baseline at all follow-up surveys. Particularly strong improvements were seen in SAQ scores angina frequency and quality of life. Binary regressions showed different statistically significant predictors in the respective models. Conclusions Following coronary revascularization with BVS strong decrease in self-reported angina frequency and increase of self-reported quality of life were observed with continuous improvements over two years of follow-up. Trial registration ClinicalTrials.gov Identifier: NCT02066623.https://doi.org/10.1186/s12872-022-02815-2Coronary artery diseaseQuality of lifeStentsBioresorbable vascular scaffold |
| spellingShingle | Kathrin Pahmeier Silke Neusser Christian Hamm Johannes Kastner Jochen Wöhrle Ralf Zahn Stephan Achenbach Julinda Mehilli Tommaso Gori Christoph Naber Holger Nef Till Neumann Gert Richardt Axel Schmermund Christoph Claas Thomas Riemer Janine Biermann-Stallwitz For the GABI-R Study Group Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry BMC Cardiovascular Disorders Coronary artery disease Quality of life Stents Bioresorbable vascular scaffold |
| title | Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry |
| title_full | Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry |
| title_fullStr | Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry |
| title_full_unstemmed | Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry |
| title_short | Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry |
| title_sort | quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold absorb™ 2 year results from the gabi r registry |
| topic | Coronary artery disease Quality of life Stents Bioresorbable vascular scaffold |
| url | https://doi.org/10.1186/s12872-022-02815-2 |
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