NEK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury

NEK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury

As one of the most common causes of mortality and disability, traumatic brain injury (TBI) is a huge psychological and economic burden to patients, families, and societies worldwide. Neuroinflammation reduction may be a favorable option to alleviate secondary brain injuries and ameliorate the outcom...

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Bibliographic Details
Main Authors: Yuhua Chen, Jiao Meng, Fangfang Bi, Hua Li, Cuicui Chang, Chen Ji, Wei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
traumatic brain injury
NLRP3 inflammasome
NEK7
caspase-1 activation
pyroptosis
potassium efflux
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00202/full

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