Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo
Abstract Background Chronic kidney disease (CKD) is a global challenge. CKD prevalence estimation is central to management strategies and prevention. It is necessary to predict end stage kidney disease (ESKD) and, subsequently, the burden for healthcare systems. In this study we characterize CKD sta...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Nephrology |
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| Online Access: | https://doi.org/10.1186/s12882-023-03056-x |
| _version_ | 1797946040859492352 |
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| author | Jan Dominik Kampmann James Goya Heaf Christian Backer Mogensen Hans Mickley Donna Lykke Wolff Frans Brandt |
| author_facet | Jan Dominik Kampmann James Goya Heaf Christian Backer Mogensen Hans Mickley Donna Lykke Wolff Frans Brandt |
| author_sort | Jan Dominik Kampmann |
| collection | DOAJ |
| description | Abstract Background Chronic kidney disease (CKD) is a global challenge. CKD prevalence estimation is central to management strategies and prevention. It is necessary to predict end stage kidney disease (ESKD) and, subsequently, the burden for healthcare systems. In this study we characterize CKD stage 3–5 prevalence and incidence in a cohort covering the majority of the Region of Southern Denmark and investigate individuals’ demographic, socioeconomic, and comorbidity status. Methods We used data from the Kidney Disease Cohort (KidDiCo) combining laboratory data from Southern Denmark with Danish national databases. Chronic kidney disease was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Results The prevalence varied between 4.83 and 4.98% and incidence rate of CKD was 0.49%/year. The median age was 76.4 years. The proportion of individuals with CKD stage 3–5 in the entire population increased consistently with age. The percentage of women in the CKD 3–5 group was higher than in the background population. Diabetes mellitus, hypertension and cardiovascular disease were more prominent in patients with CKD. CKD stage 5 and ESKD were more frequent as incident CKD stages in the 18–49 year olds when compared to older individuals. CKD patients tended to have a lower socioeconomic status. Conclusion Chronic kidney disease stage 3–5 is common, especially in the elderly. Patients with CKD stage 3–5 are predominantly female. The KidDiCo data suggests an association between lower socioeconomic status and prevalence of CKD. |
| first_indexed | 2024-04-10T21:04:37Z |
| format | Article |
| id | doaj.art-b9fe8e7f97674f819fdffbc2ce9c6e6a |
| institution | Directory Open Access Journal |
| issn | 1471-2369 |
| language | English |
| last_indexed | 2024-04-10T21:04:37Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Nephrology |
| spelling | doaj.art-b9fe8e7f97674f819fdffbc2ce9c6e6a2023-01-22T12:06:58ZengBMCBMC Nephrology1471-23692023-01-012411910.1186/s12882-023-03056-xPrevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCoJan Dominik Kampmann0James Goya Heaf1Christian Backer Mogensen2Hans Mickley3Donna Lykke Wolff4Frans Brandt5Department of Internal Medicine, University Hospital of Southern DenmarkDepartment of Medicine, Zealand University HospitalInstitute of Regional Health Research, University of Southern DenmarkDepartment of Cardiology, Odense University HospitalDepartment of Internal Medicine, University Hospital of Southern DenmarkDepartment of Internal Medicine, University Hospital of Southern DenmarkAbstract Background Chronic kidney disease (CKD) is a global challenge. CKD prevalence estimation is central to management strategies and prevention. It is necessary to predict end stage kidney disease (ESKD) and, subsequently, the burden for healthcare systems. In this study we characterize CKD stage 3–5 prevalence and incidence in a cohort covering the majority of the Region of Southern Denmark and investigate individuals’ demographic, socioeconomic, and comorbidity status. Methods We used data from the Kidney Disease Cohort (KidDiCo) combining laboratory data from Southern Denmark with Danish national databases. Chronic kidney disease was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Results The prevalence varied between 4.83 and 4.98% and incidence rate of CKD was 0.49%/year. The median age was 76.4 years. The proportion of individuals with CKD stage 3–5 in the entire population increased consistently with age. The percentage of women in the CKD 3–5 group was higher than in the background population. Diabetes mellitus, hypertension and cardiovascular disease were more prominent in patients with CKD. CKD stage 5 and ESKD were more frequent as incident CKD stages in the 18–49 year olds when compared to older individuals. CKD patients tended to have a lower socioeconomic status. Conclusion Chronic kidney disease stage 3–5 is common, especially in the elderly. Patients with CKD stage 3–5 are predominantly female. The KidDiCo data suggests an association between lower socioeconomic status and prevalence of CKD.https://doi.org/10.1186/s12882-023-03056-xChronic kidney DiseaseEpidemiologyPrevalenceSocioeconomics |
| spellingShingle | Jan Dominik Kampmann James Goya Heaf Christian Backer Mogensen Hans Mickley Donna Lykke Wolff Frans Brandt Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo BMC Nephrology Chronic kidney Disease Epidemiology Prevalence Socioeconomics |
| title | Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo |
| title_full | Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo |
| title_fullStr | Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo |
| title_full_unstemmed | Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo |
| title_short | Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo |
| title_sort | prevalence and incidence of chronic kidney disease stage 3 5 results from kiddico |
| topic | Chronic kidney Disease Epidemiology Prevalence Socioeconomics |
| url | https://doi.org/10.1186/s12882-023-03056-x |
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