Mouse B2 SINE elements function as IFN-inducible enhancers

Mouse B2 SINE elements function as IFN-inducible enhancers

Regulatory networks underlying innate immunity continually face selective pressures to adapt to new and evolving pathogens. Transposable elements (TEs) can affect immune gene expression as a source of inducible regulatory elements, but the significance of these elements in facilitating evolutionary...

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Bibliographic Details
Main Authors: Isabella Horton, Conor J Kelly, Adam Dziulko, David M Simpson, Edward B Chuong
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
interferon
transposon
gene regulation
Online Access:https://elifesciences.org/articles/82617

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