Chemosensory Contributions of E-Cigarette Additives on Nicotine Use
While rates of smoking combustible cigarettes in the United States have trended down in recent years, use of electronic cigarettes (e-cigarettes) has dramatically increased, especially among adolescents. The vast majority of e-cigarette users consume “flavored” products that contain a variety of che...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.893587/full |
| _version_ | 1811218401875460096 |
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| author | Natalie L. Johnson Theresa Patten Theresa Patten Minghong Ma Mariella De Biasi Mariella De Biasi Mariella De Biasi Daniel W. Wesson |
| author_facet | Natalie L. Johnson Theresa Patten Theresa Patten Minghong Ma Mariella De Biasi Mariella De Biasi Mariella De Biasi Daniel W. Wesson |
| author_sort | Natalie L. Johnson |
| collection | DOAJ |
| description | While rates of smoking combustible cigarettes in the United States have trended down in recent years, use of electronic cigarettes (e-cigarettes) has dramatically increased, especially among adolescents. The vast majority of e-cigarette users consume “flavored” products that contain a variety of chemosensory-rich additives, and recent literature suggests that these additives have led to the current “teen vaping epidemic.” This review, covering research from both human and rodent models, provides a comprehensive overview of the sensory implications of e-cigarette additives and what is currently known about their impact on nicotine use. In doing so, we specifically address the oronasal sensory contributions of e-cigarette additives. Finally, we summarize the existing gaps in the field and highlight future directions needed to better understand the powerful influence of these additives on nicotine use. |
| first_indexed | 2024-04-12T07:09:50Z |
| format | Article |
| id | doaj.art-ba048b612ca24db28b3f2645ce329af5 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-12T07:09:50Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-ba048b612ca24db28b3f2645ce329af52022-12-22T03:42:41ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2022-07-011610.3389/fnins.2022.893587893587Chemosensory Contributions of E-Cigarette Additives on Nicotine UseNatalie L. Johnson0Theresa Patten1Theresa Patten2Minghong Ma3Mariella De Biasi4Mariella De Biasi5Mariella De Biasi6Daniel W. Wesson7Department of Pharmacology and Therapeutics, Center for Smell and Taste, Center for Addiction Research and Education, University of Florida, Gainesville, FL, United StatesDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesPharmacology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesPharmacology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Pharmacology and Therapeutics, Center for Smell and Taste, Center for Addiction Research and Education, University of Florida, Gainesville, FL, United StatesWhile rates of smoking combustible cigarettes in the United States have trended down in recent years, use of electronic cigarettes (e-cigarettes) has dramatically increased, especially among adolescents. The vast majority of e-cigarette users consume “flavored” products that contain a variety of chemosensory-rich additives, and recent literature suggests that these additives have led to the current “teen vaping epidemic.” This review, covering research from both human and rodent models, provides a comprehensive overview of the sensory implications of e-cigarette additives and what is currently known about their impact on nicotine use. In doing so, we specifically address the oronasal sensory contributions of e-cigarette additives. Finally, we summarize the existing gaps in the field and highlight future directions needed to better understand the powerful influence of these additives on nicotine use.https://www.frontiersin.org/articles/10.3389/fnins.2022.893587/fullflavorsTRPA1TRPM8addictionmenthololfactory |
| spellingShingle | Natalie L. Johnson Theresa Patten Theresa Patten Minghong Ma Mariella De Biasi Mariella De Biasi Mariella De Biasi Daniel W. Wesson Chemosensory Contributions of E-Cigarette Additives on Nicotine Use Frontiers in Neuroscience flavors TRPA1 TRPM8 addiction menthol olfactory |
| title | Chemosensory Contributions of E-Cigarette Additives on Nicotine Use |
| title_full | Chemosensory Contributions of E-Cigarette Additives on Nicotine Use |
| title_fullStr | Chemosensory Contributions of E-Cigarette Additives on Nicotine Use |
| title_full_unstemmed | Chemosensory Contributions of E-Cigarette Additives on Nicotine Use |
| title_short | Chemosensory Contributions of E-Cigarette Additives on Nicotine Use |
| title_sort | chemosensory contributions of e cigarette additives on nicotine use |
| topic | flavors TRPA1 TRPM8 addiction menthol olfactory |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2022.893587/full |
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