Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus

Atherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as increasing coagulation, impaired fibrinolysis, endothelial dysfunction, a...

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Main Authors: Jin Hwa Kim, Hak Yeon Bae, Sang Yong Kim
Format: Article
Language:English
Published: Korean Diabetes Association 2013-12-01
Series:Diabetes & Metabolism Journal
Subjects:
Online Access:http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-37-423.pdf
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author Jin Hwa Kim
Hak Yeon Bae
Sang Yong Kim
author_facet Jin Hwa Kim
Hak Yeon Bae
Sang Yong Kim
author_sort Jin Hwa Kim
collection DOAJ
description Atherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as increasing coagulation, impaired fibrinolysis, endothelial dysfunction, and platelet hyperreactivity. Among the factors that contribute to the prothrombotic status in diabetes, altered platelet function plays a crucial role. Although understanding platelet function abnormalities in diabetes still remains as a challenge, more attention should be focused on platelet function for effective management and the prediction of atherothrombotic events in diabetic patients. This review will provide an overview on the current status of knowledge of platelet function abnormalities and clinical marker of platelet hyperreactivity in patients with diabetes.
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spelling doaj.art-ba06699e7e354f769712df6445886efd2022-12-22T00:01:41ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872013-12-0137642342810.4093/dmj.2013.37.6.4232117Clinical Marker of Platelet Hyperreactivity in Diabetes MellitusJin Hwa KimHak Yeon BaeSang Yong KimAtherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as increasing coagulation, impaired fibrinolysis, endothelial dysfunction, and platelet hyperreactivity. Among the factors that contribute to the prothrombotic status in diabetes, altered platelet function plays a crucial role. Although understanding platelet function abnormalities in diabetes still remains as a challenge, more attention should be focused on platelet function for effective management and the prediction of atherothrombotic events in diabetic patients. This review will provide an overview on the current status of knowledge of platelet function abnormalities and clinical marker of platelet hyperreactivity in patients with diabetes.http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-37-423.pdfBlood plateletsDiabetes mellitusHyperreactivityMarker
spellingShingle Jin Hwa Kim
Hak Yeon Bae
Sang Yong Kim
Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
Diabetes & Metabolism Journal
Blood platelets
Diabetes mellitus
Hyperreactivity
Marker
title Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
title_full Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
title_fullStr Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
title_full_unstemmed Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
title_short Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
title_sort clinical marker of platelet hyperreactivity in diabetes mellitus
topic Blood platelets
Diabetes mellitus
Hyperreactivity
Marker
url http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-37-423.pdf
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