Novel <i>PRUNE2</i> Germline Mutations in Aggressive and Benign Parathyroid Neoplasms

Novel <i>PRUNE2</i> Germline Mutations in Aggressive and Benign Parathyroid Neoplasms

Parathyroid tumors are mostly sporadic but can also occur in familial forms, including different kinds of genetic syndromes with varying phenotypes and penetrance. Recently, somatic mutations of the tumor suppressor gene <i>PRUNE2</i> were found to be frequent in parathyroid cancer (PC)....

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Bibliographic Details
Main Authors: Sara Storvall, Eeva Ryhänen, Auli Karhu, Camilla Schalin-Jäntti
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
primary hyperparathyroidism
parathyroid carcinoma
whole-exome sequencing
PRUNE2
germline
mutation
Online Access:https://www.mdpi.com/2072-6694/15/5/1405

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