the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm
One of the best-studied responses of cognitive evoked potentials is a so-called 'P300', the late positive wave complex that occurs about 300-500 ms after the stimulus. It is obtained when the subject's attention is focused on a signal that is rare, especially if the signal has a motiv...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Medicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društva
2015-01-01
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| Series: | Praxis Medica |
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| Online Access: | http://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2015/0350-87731502093B.pdf |
| _version_ | 1819211302478807040 |
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| author | Biševac B. Popović Lj. Milanović Z. Nestorović V. Smiljić S. Dejanović M. Filipović-Danić S. Mitrović V. Mirić M. |
| author_facet | Biševac B. Popović Lj. Milanović Z. Nestorović V. Smiljić S. Dejanović M. Filipović-Danić S. Mitrović V. Mirić M. |
| author_sort | Biševac B. |
| collection | DOAJ |
| description | One of the best-studied responses of cognitive evoked potentials is a so-called 'P300', the late positive wave complex that occurs about 300-500 ms after the stimulus. It is obtained when the subject's attention is focused on a signal that is rare, especially if the signal has a motivational or emotional meaning. In the study of P300 potential, we followed the variations of potential amplitude and latency, so the objective was to examine whether there is a difference in Fz and Cz amplitudes of auditory induced cognitive evoked P300 potential depending on the performance of oddball tasks, both in male and female subjects. The study included 60 subjects (30 female respondents and 30 male respondents). P300 potential is induced by the auditory 'oddball' paradigm with 80% of non-target and 20% of target stimuli that are presented to the patient through headphones. The target tones are high tones of 2000 Hz. The standard, 1000 Hz tones the respondent should ignore but when he hears the target tones the respondent should press the button on the special handle. The value of Fz and Cz amplitudes both in male and female subjects obtained in the classical 'oddball' paradigm when the subject reacted to the signal by pressing the key with the dominant (right) arm were statistically significantly lower (p>0,05) than the values of Fz and Cz amplitudes obtained when the key was pressed by the non-dominant hand. Based on this experiment it can be concluded that both in male and female subjects the performance of oddball tasks does not affect the amplitude of P300 cognitive evoked potentials. |
| first_indexed | 2024-12-23T06:24:55Z |
| format | Article |
| id | doaj.art-ba07484b301a47c390cf5d37f64d0bc6 |
| institution | Directory Open Access Journal |
| issn | 0350-8773 |
| language | English |
| last_indexed | 2024-12-23T06:24:55Z |
| publishDate | 2015-01-01 |
| publisher | Medicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društva |
| record_format | Article |
| series | Praxis Medica |
| spelling | doaj.art-ba07484b301a47c390cf5d37f64d0bc62022-12-21T17:57:05ZengMedicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društvaPraxis Medica0350-87732015-01-01442939610.5937/pramed1502093B0350-87731502093Bthe variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigmBiševac B.0Popović Lj.1Milanović Z.2Nestorović V.3Smiljić S.4Dejanović M.5Filipović-Danić S.6Mitrović V.7Mirić M.8Institute of physiology, Medical faculty, Kosovska MitrovicaInstitute of patophysiology, Medical faculty, Kosovska MitrovicaInstitute of physiology, Medical faculty, Kosovska MitrovicaInstitute of physiology, Medical faculty, Kosovska MitrovicaInstitute of physiology, Medical faculty, Kosovska MitrovicaInstitute of physiology, Medical faculty, Kosovska MitrovicaUniversity of Priština, Faculty of Medicine, Kosovska Mitrovica, SerbiaUniversity of Priština, Faculty of Medicine, Kosovska Mitrovica, SerbiaUniversity of Priština, Faculty of Medicine, Kosovska Mitrovica, SerbiaOne of the best-studied responses of cognitive evoked potentials is a so-called 'P300', the late positive wave complex that occurs about 300-500 ms after the stimulus. It is obtained when the subject's attention is focused on a signal that is rare, especially if the signal has a motivational or emotional meaning. In the study of P300 potential, we followed the variations of potential amplitude and latency, so the objective was to examine whether there is a difference in Fz and Cz amplitudes of auditory induced cognitive evoked P300 potential depending on the performance of oddball tasks, both in male and female subjects. The study included 60 subjects (30 female respondents and 30 male respondents). P300 potential is induced by the auditory 'oddball' paradigm with 80% of non-target and 20% of target stimuli that are presented to the patient through headphones. The target tones are high tones of 2000 Hz. The standard, 1000 Hz tones the respondent should ignore but when he hears the target tones the respondent should press the button on the special handle. The value of Fz and Cz amplitudes both in male and female subjects obtained in the classical 'oddball' paradigm when the subject reacted to the signal by pressing the key with the dominant (right) arm were statistically significantly lower (p>0,05) than the values of Fz and Cz amplitudes obtained when the key was pressed by the non-dominant hand. Based on this experiment it can be concluded that both in male and female subjects the performance of oddball tasks does not affect the amplitude of P300 cognitive evoked potentials.http://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2015/0350-87731502093B.pdfP300cognitive evoked potentialsoddball paradigm |
| spellingShingle | Biševac B. Popović Lj. Milanović Z. Nestorović V. Smiljić S. Dejanović M. Filipović-Danić S. Mitrović V. Mirić M. the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm Praxis Medica P300 cognitive evoked potentials oddball paradigm |
| title | the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm |
| title_full | the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm |
| title_fullStr | the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm |
| title_full_unstemmed | the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm |
| title_short | the variability in P300 cognitive evoked potential amplitude in the auditory oddball paradigm |
| title_sort | variability in p300 cognitive evoked potential amplitude in the auditory oddball paradigm |
| topic | P300 cognitive evoked potentials oddball paradigm |
| url | http://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2015/0350-87731502093B.pdf |
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