Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study.
<h4>Background</h4>Admission to hospital introduces risks for people with Parkinson's disease in maintaining continuity of their highly individualized medication regimens, which increases their risk of medication errors. This is of particular concern as omitted medications and irreg...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0267969 |
| _version_ | 1811295428494229504 |
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| author | Michael Bakker Michaela E Johnson Lauren Corre Deanna N Mill Xingzhuo Li Richard J Woodman Jacinta L Johnson |
| author_facet | Michael Bakker Michaela E Johnson Lauren Corre Deanna N Mill Xingzhuo Li Richard J Woodman Jacinta L Johnson |
| author_sort | Michael Bakker |
| collection | DOAJ |
| description | <h4>Background</h4>Admission to hospital introduces risks for people with Parkinson's disease in maintaining continuity of their highly individualized medication regimens, which increases their risk of medication errors. This is of particular concern as omitted medications and irregular dosing can cause an immediate increase in an individual's symptoms as well as other adverse outcomes such as swallowing difficulties, aspiration pneumonia, frozen gait and even potentially fatal neuroleptic malignant type syndrome.<h4>Objective</h4>To determine the occurrence and identify factors that contribute to Parkinson's medication errors in Australian hospitals.<h4>Methods</h4>A retrospective discharge diagnosis code search identified all admissions for people with Parkinson's disease to three tertiary metropolitan hospitals in South Australia, Australia over a 3-year period. Of the 405 case notes reviewed 351 admissions met our inclusion criteria.<h4>Results</h4>Medication prescribing (30.5%) and administration (85%) errors during admission were extremely common, with the most frequent errors related to administration of levodopa preparations (83%). A higher levodopa equivalent dosage, patients with a modified swallowing status or nil by mouth order during admission, and patients who did not have a pharmacist led medication history within 24 hours of admission had significantly higher rates of medication errors.<h4>Conclusions</h4>This study identified 3 major independent factors that increased the risk of errors during medication management for people with Parkinson's disease during hospitalization. Thus, targeting these areas for preventative interventions have the greatest chance of producing a clinically meaningful impact on the number of hospital medication errors occurring in the Parkinson's population. |
| first_indexed | 2024-04-13T05:32:24Z |
| format | Article |
| id | doaj.art-ba0cd36683794663b5a6d2c448188be3 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T05:32:24Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-ba0cd36683794663b5a6d2c448188be32022-12-22T03:00:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01175e026796910.1371/journal.pone.0267969Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study.Michael BakkerMichaela E JohnsonLauren CorreDeanna N MillXingzhuo LiRichard J WoodmanJacinta L Johnson<h4>Background</h4>Admission to hospital introduces risks for people with Parkinson's disease in maintaining continuity of their highly individualized medication regimens, which increases their risk of medication errors. This is of particular concern as omitted medications and irregular dosing can cause an immediate increase in an individual's symptoms as well as other adverse outcomes such as swallowing difficulties, aspiration pneumonia, frozen gait and even potentially fatal neuroleptic malignant type syndrome.<h4>Objective</h4>To determine the occurrence and identify factors that contribute to Parkinson's medication errors in Australian hospitals.<h4>Methods</h4>A retrospective discharge diagnosis code search identified all admissions for people with Parkinson's disease to three tertiary metropolitan hospitals in South Australia, Australia over a 3-year period. Of the 405 case notes reviewed 351 admissions met our inclusion criteria.<h4>Results</h4>Medication prescribing (30.5%) and administration (85%) errors during admission were extremely common, with the most frequent errors related to administration of levodopa preparations (83%). A higher levodopa equivalent dosage, patients with a modified swallowing status or nil by mouth order during admission, and patients who did not have a pharmacist led medication history within 24 hours of admission had significantly higher rates of medication errors.<h4>Conclusions</h4>This study identified 3 major independent factors that increased the risk of errors during medication management for people with Parkinson's disease during hospitalization. Thus, targeting these areas for preventative interventions have the greatest chance of producing a clinically meaningful impact on the number of hospital medication errors occurring in the Parkinson's population.https://doi.org/10.1371/journal.pone.0267969 |
| spellingShingle | Michael Bakker Michaela E Johnson Lauren Corre Deanna N Mill Xingzhuo Li Richard J Woodman Jacinta L Johnson Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study. PLoS ONE |
| title | Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study. |
| title_full | Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study. |
| title_fullStr | Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study. |
| title_full_unstemmed | Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study. |
| title_short | Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson's disease population: A 3-year, multi-center study. |
| title_sort | identifying rates and risk factors for medication errors during hospitalization in the australian parkinson s disease population a 3 year multi center study |
| url | https://doi.org/10.1371/journal.pone.0267969 |
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