Reduced glutathione and glutathione disulfide in the blood of glucose-6-phosphate dehydrogenase-deficient newborns

Reduced glutathione and glutathione disulfide in the blood of glucose-6-phosphate dehydrogenase-deficient newborns

Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is commonly detected during mass screening for neonatal disease. We developed a method to measure reduced glutathione (GSH) and glutathione disulfide (GSSG) using tandem mass spectrometry (MS/MS) for detecting G6PD deficiency. M...

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Bibliographic Details
Main Authors: Zhen-hua Gong, Guo-li Tian, Qi-wei Huang, Yan-min Wang, Hong-ping Xu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Pediatrics
Subjects:
Glucose-6-phosphate dehydrogenase deficiency
Blood
Glutathione
Tandem mass spectrometry
Online Access:http://link.springer.com/article/10.1186/s12887-017-0920-y

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