Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients

BACKGROUND: Telomeres are protective caps consisted of specific tandem repeats (5′-TTAGGG-3′). Shortening of telomeres at each cell division is known as "mitotic clock" of the cells, which renders telomeres as important regulators of lifespan. TRF2 is one of the critical members of shelter...

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Bibliographic Details
Main Authors: Sevgi Ozden, Pinar Mega Tiber, Zerrin Ozgen, Hazan Ozyurt, Nedime Serakinci, Oya Orun
Format: Article
Language:English
Published: BMC 2014-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100055&lng=en&tlng=en