Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report

Abstract Background Compared to other intravenous anesthetics, availability of a specific antagonist flumazenil is a clear advantage of remimazolam. We report a patient who could be rapidly woken up when laryngoscopy and tracheal intubation were unexpectedly difficult. Case presentation A 62-year-ol...

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Main Authors: Shota Sekimoto, Shuya Kiyama, Shoichi Uezono
Format: Article
Language:English
Published: SpringerOpen 2023-07-01
Series:JA Clinical Reports
Subjects:
Online Access:https://doi.org/10.1186/s40981-023-00638-4
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author Shota Sekimoto
Shuya Kiyama
Shoichi Uezono
author_facet Shota Sekimoto
Shuya Kiyama
Shoichi Uezono
author_sort Shota Sekimoto
collection DOAJ
description Abstract Background Compared to other intravenous anesthetics, availability of a specific antagonist flumazenil is a clear advantage of remimazolam. We report a patient who could be rapidly woken up when laryngoscopy and tracheal intubation were unexpectedly difficult. Case presentation A 62-year-old man was scheduled to have resection of a small gingival tumor. Preoperative airway examination was unremarkable except for an omega-shaped epiglottis. Anesthesia was induced with remifentanil/remimazolam infusion and rocuronium. A small omega-shaped edematous epiglottis precluded identification of glottis. Consciousness and spontaneous ventilation were rapidly restored after administration of flumazenil and sugammadex. Tracheostomy was done under local anesthesia while the patient breathed spontaneously. Conclusions Remimazolam can be a reasonable induction agent when there are concerns regarding airway management. Avoiding repeated airway manipulations is extremely important to prevent deterioration into a “cannot intubate, cannot ventilate (CICV)” emergency.
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spelling doaj.art-ba10380fd74f4ef39946823875d094a92023-07-30T11:09:42ZengSpringerOpenJA Clinical Reports2363-90242023-07-01911410.1186/s40981-023-00638-4Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case reportShota Sekimoto0Shuya Kiyama1Shoichi Uezono2Department of Anesthesiology, School of Medicine, The Jikei UniversityDepartment of Anesthesiology, School of Medicine, The Jikei UniversityDepartment of Anesthesiology, School of Medicine, The Jikei UniversityAbstract Background Compared to other intravenous anesthetics, availability of a specific antagonist flumazenil is a clear advantage of remimazolam. We report a patient who could be rapidly woken up when laryngoscopy and tracheal intubation were unexpectedly difficult. Case presentation A 62-year-old man was scheduled to have resection of a small gingival tumor. Preoperative airway examination was unremarkable except for an omega-shaped epiglottis. Anesthesia was induced with remifentanil/remimazolam infusion and rocuronium. A small omega-shaped edematous epiglottis precluded identification of glottis. Consciousness and spontaneous ventilation were rapidly restored after administration of flumazenil and sugammadex. Tracheostomy was done under local anesthesia while the patient breathed spontaneously. Conclusions Remimazolam can be a reasonable induction agent when there are concerns regarding airway management. Avoiding repeated airway manipulations is extremely important to prevent deterioration into a “cannot intubate, cannot ventilate (CICV)” emergency.https://doi.org/10.1186/s40981-023-00638-4RemimazolamFlumazenilEpiglottisDifficult laryngoscopyCICV
spellingShingle Shota Sekimoto
Shuya Kiyama
Shoichi Uezono
Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report
JA Clinical Reports
Remimazolam
Flumazenil
Epiglottis
Difficult laryngoscopy
CICV
title Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report
title_full Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report
title_fullStr Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report
title_full_unstemmed Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report
title_short Successful reversal of remimazolam anesthesia in a “cannot intubate, can ventilate” situation: a case report
title_sort successful reversal of remimazolam anesthesia in a cannot intubate can ventilate situation a case report
topic Remimazolam
Flumazenil
Epiglottis
Difficult laryngoscopy
CICV
url https://doi.org/10.1186/s40981-023-00638-4
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AT shoichiuezono successfulreversalofremimazolamanesthesiainacannotintubatecanventilatesituationacasereport