Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>

As a prevalent medical problem that burdens millions of patients across the world, chronic wounds pose a challenge to the healthcare system. These wounds, often existing as a comorbidity, are vulnerable to infections. Consequently, infections hinder the healing process and complicate clinical manage...

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Main Authors: Jaeson D. Chin, Lei Zhao, Trenton G. Mayberry, Braydon C. Cowan, Mark R. Wakefield, Yujiang Fang
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/6/1721
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author Jaeson D. Chin
Lei Zhao
Trenton G. Mayberry
Braydon C. Cowan
Mark R. Wakefield
Yujiang Fang
author_facet Jaeson D. Chin
Lei Zhao
Trenton G. Mayberry
Braydon C. Cowan
Mark R. Wakefield
Yujiang Fang
author_sort Jaeson D. Chin
collection DOAJ
description As a prevalent medical problem that burdens millions of patients across the world, chronic wounds pose a challenge to the healthcare system. These wounds, often existing as a comorbidity, are vulnerable to infections. Consequently, infections hinder the healing process and complicate clinical management and treatment. While antibiotic drugs remain a popular treatment for infected chronic wounds, the recent rise of antibiotic-resistant strains has hastened the need for alternative treatments. Future impacts of chronic wounds are likely to increase with aging populations and growing obesity rates. With the need for more effective novel treatments, promising research into various wound therapies has seen an increased demand. This review summarizes photodynamic therapy, probiotics, acetic acid, and essential oil studies as developing antibiotic-free treatments for chronic wounds infected with <i>Pseudomonas aeruginosa</i>. Clinicians may find this review informative by gaining a better understanding of the state of current research into various antibiotic-free treatments. Furthermore. this review provides clinical significance, as clinicians may seek to implement photodynamic therapy, probiotics, acetic acid, or essential oils into their own practice.
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spelling doaj.art-ba136ad04a0f48c7a8d70d9d555bc2c32023-11-18T12:05:33ZengMDPI AGPharmaceutics1999-49232023-06-01156172110.3390/pharmaceutics15061721Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>Jaeson D. Chin0Lei Zhao1Trenton G. Mayberry2Braydon C. Cowan3Mark R. Wakefield4Yujiang Fang5Department of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA 50312, USAThe Department of Respiratory Medicine, The Second People’s Hospital of Hefei and Hefei Hospital Affiliated to Anhui Medical University, Hefei 230002, ChinaDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USADepartment of Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USADepartment of Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USADepartment of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA 50312, USAAs a prevalent medical problem that burdens millions of patients across the world, chronic wounds pose a challenge to the healthcare system. These wounds, often existing as a comorbidity, are vulnerable to infections. Consequently, infections hinder the healing process and complicate clinical management and treatment. While antibiotic drugs remain a popular treatment for infected chronic wounds, the recent rise of antibiotic-resistant strains has hastened the need for alternative treatments. Future impacts of chronic wounds are likely to increase with aging populations and growing obesity rates. With the need for more effective novel treatments, promising research into various wound therapies has seen an increased demand. This review summarizes photodynamic therapy, probiotics, acetic acid, and essential oil studies as developing antibiotic-free treatments for chronic wounds infected with <i>Pseudomonas aeruginosa</i>. Clinicians may find this review informative by gaining a better understanding of the state of current research into various antibiotic-free treatments. Furthermore. this review provides clinical significance, as clinicians may seek to implement photodynamic therapy, probiotics, acetic acid, or essential oils into their own practice.https://www.mdpi.com/1999-4923/15/6/1721chronic woundsphotodynamic therapyprobioticsacetic acid<i>Pseudomonas aeruginosa</i>
spellingShingle Jaeson D. Chin
Lei Zhao
Trenton G. Mayberry
Braydon C. Cowan
Mark R. Wakefield
Yujiang Fang
Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>
Pharmaceutics
chronic wounds
photodynamic therapy
probiotics
acetic acid
<i>Pseudomonas aeruginosa</i>
title Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>
title_full Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>
title_fullStr Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>
title_full_unstemmed Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>
title_short Photodynamic Therapy, Probiotics, Acetic Acid, and Essential Oil in the Treatment of Chronic Wounds Infected with <i>Pseudomonas aeruginosa</i>
title_sort photodynamic therapy probiotics acetic acid and essential oil in the treatment of chronic wounds infected with i pseudomonas aeruginosa i
topic chronic wounds
photodynamic therapy
probiotics
acetic acid
<i>Pseudomonas aeruginosa</i>
url https://www.mdpi.com/1999-4923/15/6/1721
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