Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan

Charged particles can achieve better dose distribution and higher biological effectiveness compared to photon radiotherapy. Carbon ions are considered an optimal candidate for cancer treatment using particles. The National Institute of Radiological Sciences (NIRS) in Chiba, Japan was the first radio...

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Main Authors: Osama Mohamad, Hirokazu Makishima, Tadashi Kamada
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/3/66
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author Osama Mohamad
Hirokazu Makishima
Tadashi Kamada
author_facet Osama Mohamad
Hirokazu Makishima
Tadashi Kamada
author_sort Osama Mohamad
collection DOAJ
description Charged particles can achieve better dose distribution and higher biological effectiveness compared to photon radiotherapy. Carbon ions are considered an optimal candidate for cancer treatment using particles. The National Institute of Radiological Sciences (NIRS) in Chiba, Japan was the first radiotherapy hospital dedicated for carbon ion treatments in the world. Since its establishment in 1994, the NIRS has pioneered this therapy with more than 69 clinical trials so far, and hundreds of ancillary projects in physics and radiobiology. In this review, we will discuss the evolution of carbon ion radiotherapy at the NIRS and some of the current and future projects in the field.
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spelling doaj.art-ba140bad3dac46cba1bbeb4f8b9d7d2e2023-09-03T03:54:37ZengMDPI AGCancers2072-66942018-03-011036610.3390/cancers10030066cancers10030066Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in JapanOsama Mohamad0Hirokazu Makishima1Tadashi Kamada2Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, JapanHospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, JapanHospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, JapanCharged particles can achieve better dose distribution and higher biological effectiveness compared to photon radiotherapy. Carbon ions are considered an optimal candidate for cancer treatment using particles. The National Institute of Radiological Sciences (NIRS) in Chiba, Japan was the first radiotherapy hospital dedicated for carbon ion treatments in the world. Since its establishment in 1994, the NIRS has pioneered this therapy with more than 69 clinical trials so far, and hundreds of ancillary projects in physics and radiobiology. In this review, we will discuss the evolution of carbon ion radiotherapy at the NIRS and some of the current and future projects in the field.http://www.mdpi.com/2072-6694/10/3/66carbon ion radiotherapyCIRTNational Institute of Radiological SciencesNIRSparticle therapy
spellingShingle Osama Mohamad
Hirokazu Makishima
Tadashi Kamada
Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan
Cancers
carbon ion radiotherapy
CIRT
National Institute of Radiological Sciences
NIRS
particle therapy
title Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan
title_full Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan
title_fullStr Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan
title_full_unstemmed Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan
title_short Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan
title_sort evolution of carbon ion radiotherapy at the national institute of radiological sciences in japan
topic carbon ion radiotherapy
CIRT
National Institute of Radiological Sciences
NIRS
particle therapy
url http://www.mdpi.com/2072-6694/10/3/66
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AT hirokazumakishima evolutionofcarbonionradiotherapyatthenationalinstituteofradiologicalsciencesinjapan
AT tadashikamada evolutionofcarbonionradiotherapyatthenationalinstituteofradiologicalsciencesinjapan