Cytotoxicity of Amphotericin B and AmBisome: In Silico and In Vivo Evaluation Employing the Chick Embryo Model

Cytotoxicity of Amphotericin B and AmBisome: In Silico and In Vivo Evaluation Employing the Chick Embryo Model

Leishmaniasis has been identified as a significant disease in tropical and subtropical regions of the world, with Iran being one of the disease-endemic areas. Various treatments have been applied for this disease, and amphotericin B (Amp B) is the second line of treatment. Side effects of this drug...

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Bibliographic Details
Main Authors: Ahmad Khosravi, Iraj Sharifi, Hadi Tavakkoli, Elaheh Molaakbari, Sina Bahraminegad, Ehsan Salarkia, Fatemeh Seyedi, Alireza Keyhani, Zohreh Salari, Fatemeh Sharifi, Mehdi Bamorovat, Ali Afgar, Shahriar Dabiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
leishmaniasis
amphotericin B
toxicity
apoptosis
angiogenesis
in silico
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.860598/full

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