Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses.

Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses.

During fetal development neural-crest-derived melanoblasts migrate across the entire body surface and differentiate into melanocytes, the pigment-producing cells. Alterations in this precisely regulated process can lead to white spotting patterns. White spotting patterns in horses are a complex trai...

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Bibliographic Details
Main Authors: Regula Hauswirth, Bianca Haase, Marlis Blatter, Samantha A Brooks, Dominik Burger, Cord Drögemüller, Vincent Gerber, Diana Henke, Jozef Janda, Rony Jude, K Gary Magdesian, Jacqueline M Matthews, Pierre-André Poncet, Vilhjálmur Svansson, Teruaki Tozaki, Lorna Wilkinson-White, M Cecilia T Penedo, Stefan Rieder, Tosso Leeb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3325211?pdf=render

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