Comparative Proteomic Analysis of <i>Toxoplasma gondii</i> RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains

In <i>T. gondii</i>, as well as in other model organisms, gene knock-out using CRISPR-Cas9 is a suitable tool to identify the role of specific genes. The general consensus implies that only the gene of interest is affected by the knock-out. Is this really the case? In a previous study, w...

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Bibliographic Details
Main Authors: Kai Pascal Alexander Hänggeli, Andrew Hemphill, Norbert Müller, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache, Joachim Müller, Ghalia Boubaker
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/13/10454