Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study
Abstract Background Tomosynthesis is a recent advancement of full-field digital mammography involves transforming two-dimensional (2D) breast images into three dimensions (3D) images. It reduces the adverse effect of tissue superimposition on conventional 2D- mammography, therefore having high poten...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-06-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-023-01057-2 |
| _version_ | 1827917069693222912 |
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| author | Rasha Osama Abdel Ghany Ahmed Mohamed Abo El-Hoda Darwish Nivine Abd Elmoneim Chalabi Salma Hassan Tantawy |
| author_facet | Rasha Osama Abdel Ghany Ahmed Mohamed Abo El-Hoda Darwish Nivine Abd Elmoneim Chalabi Salma Hassan Tantawy |
| author_sort | Rasha Osama Abdel Ghany Ahmed |
| collection | DOAJ |
| description | Abstract Background Tomosynthesis is a recent advancement of full-field digital mammography involves transforming two-dimensional (2D) breast images into three dimensions (3D) images. It reduces the adverse effect of tissue superimposition on conventional 2D- mammography, therefore having high potential enhancing identification and assessment of asymmetric breast densities. The aim of the study was to assess and compare the diagnostic performance of breast ultrasound and 3D digital breast tomosynthesis in the assessment of asymmetric breast densities. Results In the current study, 80 patients with 80 mammographically and/or tomosynthesized breast asymmetries were included. The patients' ages ranged from 30 to 70 years old, with a mean age of 47.2 ± 9.2 SD. Breast ultrasound outperformed digital breast tomosynthesis in terms of diagnostic performance. Tomosynthesis had a sensitivity of 86.4%, specificity of 93.1%, positive predictive value of 82.6%, negative predictive value of 94.7%, and accuracy of 91.3% compared to ultrasounds' sensitivity of 100.00%, specificity of 93.1%, positive predictive value of 84.6%, negative predictive value of 100.00%, and accuracy of 95%. Conclusions Incorporating ultrasonography in the assessment of asymmetric breast densities outperformed tomosynthesis and shown to be more precise in characterisation of lesions underlying asymmetric breast density. |
| first_indexed | 2024-03-13T03:23:30Z |
| format | Article |
| id | doaj.art-ba1968b0610b4d588357d7ad2e7db5d3 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-03-13T03:23:30Z |
| publishDate | 2023-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-ba1968b0610b4d588357d7ad2e7db5d32023-06-25T11:12:16ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622023-06-0154111210.1186/s43055-023-01057-2Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective studyRasha Osama Abdel Ghany Ahmed0Mohamed Abo El-Hoda Darwish1Nivine Abd Elmoneim Chalabi2Salma Hassan Tantawy3Radiodiagnosis Department, Al Ahrar Teaching HospitalRadiodiagnosis Department, Faculty of Medicine, Ain Shams UniversityRadiodiagnosis Department, Faculty of Medicine, Ain Shams UniversityRadiodiagnosis Department, Faculty of Medicine, Ain Shams UniversityAbstract Background Tomosynthesis is a recent advancement of full-field digital mammography involves transforming two-dimensional (2D) breast images into three dimensions (3D) images. It reduces the adverse effect of tissue superimposition on conventional 2D- mammography, therefore having high potential enhancing identification and assessment of asymmetric breast densities. The aim of the study was to assess and compare the diagnostic performance of breast ultrasound and 3D digital breast tomosynthesis in the assessment of asymmetric breast densities. Results In the current study, 80 patients with 80 mammographically and/or tomosynthesized breast asymmetries were included. The patients' ages ranged from 30 to 70 years old, with a mean age of 47.2 ± 9.2 SD. Breast ultrasound outperformed digital breast tomosynthesis in terms of diagnostic performance. Tomosynthesis had a sensitivity of 86.4%, specificity of 93.1%, positive predictive value of 82.6%, negative predictive value of 94.7%, and accuracy of 91.3% compared to ultrasounds' sensitivity of 100.00%, specificity of 93.1%, positive predictive value of 84.6%, negative predictive value of 100.00%, and accuracy of 95%. Conclusions Incorporating ultrasonography in the assessment of asymmetric breast densities outperformed tomosynthesis and shown to be more precise in characterisation of lesions underlying asymmetric breast density.https://doi.org/10.1186/s43055-023-01057-2MammographyDBTUSBreast asymmetries |
| spellingShingle | Rasha Osama Abdel Ghany Ahmed Mohamed Abo El-Hoda Darwish Nivine Abd Elmoneim Chalabi Salma Hassan Tantawy Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study The Egyptian Journal of Radiology and Nuclear Medicine Mammography DBT US Breast asymmetries |
| title | Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study |
| title_full | Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study |
| title_fullStr | Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study |
| title_full_unstemmed | Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study |
| title_short | Role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities: a comparative prospective study |
| title_sort | role of tomosynthesis and ultrasound in the assessment of asymmetric breast densities a comparative prospective study |
| topic | Mammography DBT US Breast asymmetries |
| url | https://doi.org/10.1186/s43055-023-01057-2 |
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