Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study
Background/objective: Blood donation is considered to be a safe procedure, however, sometimes vasovagal reactions (VVRs) with various degrees of severity can occur. This paper provides an overview of the incidence of VVR with a focus on vasovagal syncope (VVS, temporary loss of consciousness), risk...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Danish |
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NITO - Bioingeniørfaglig institutt
2023-11-01
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| Series: | Bioingeniøren |
| Subjects: | |
| Online Access: | https://www.bioingenioren.no/fag/fag-oversiktsartikkel/vasovagale-reaksjoner-blant-blodgivere--forekomst-mekanismer-risikofaktore-implikasjoner-og-forebyggende-tiltak---en-litteraturstudie/ |
| _version_ | 1797324150241492992 |
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| author | Sadaf Nabi Bhatti Dorthe Charlotte Johannessen Abid Hussain Llohn Seyed Ali Mousavi |
| author_facet | Sadaf Nabi Bhatti Dorthe Charlotte Johannessen Abid Hussain Llohn Seyed Ali Mousavi |
| author_sort | Sadaf Nabi Bhatti |
| collection | DOAJ |
| description | Background/objective: Blood donation is considered to be a safe procedure, however, sometimes vasovagal reactions (VVRs) with various degrees of severity can occur. This paper provides an overview of the incidence of VVR with a focus on vasovagal syncope (VVS, temporary loss of consciousness), risk factors, and possible consequences of VVR/VVS for donors, as well as effects of interventions that are used to reduce VVR/VVS among blood donors. We also discuss mechanisms underlying VVS and evolutionary explanations for VVS.
Methods: Relevant studies were found by search in PubMed.
Results: Reported incidence of VVS varies from 0.1% to 0.5%, with higher incidence among younger and first-time donors, but mixed results have been found for gender differences: whereas some studies report higher incidence among female donors, other studies find no differences. Anxiety, fear of needles or seeing blood are frequent triggers of VVR/VVS, particularly among first-time donors. Donors who have experienced VVR/VVS are less likely to return to donate. Physiologic interventions such as pre-donation water intake and applied muscle tension during donation, alone or in combination, have shown effect in reducing VVR/VVS in several studies. Psychological interventions such as distraction and social support have also shown to reduce the risk of VVR/VVS. From an evolutionary perspective, VVS may have had a survival advantage in the distant past. |
| first_indexed | 2024-03-08T05:46:02Z |
| format | Article |
| id | doaj.art-ba1c5b70901b4300a3ebf7c05b2a2fab |
| institution | Directory Open Access Journal |
| issn | 0801-6828 1890-1875 |
| language | Danish |
| last_indexed | 2024-03-08T05:46:02Z |
| publishDate | 2023-11-01 |
| publisher | NITO - Bioingeniørfaglig institutt |
| record_format | Article |
| series | Bioingeniøren |
| spelling | doaj.art-ba1c5b70901b4300a3ebf7c05b2a2fab2024-02-05T09:52:25ZdanNITO - Bioingeniørfaglig instituttBioingeniøren0801-68281890-18752023-11-015882631 Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature studySadaf Nabi Bhatti0Dorthe Charlotte Johannessen1Abid Hussain Llohn2Seyed Ali Mousavi3Akershus universitetssykehus HFAkershus universitetssykehus HFAkershus universitetssykehus HFAkershus universitetssykehus HFBackground/objective: Blood donation is considered to be a safe procedure, however, sometimes vasovagal reactions (VVRs) with various degrees of severity can occur. This paper provides an overview of the incidence of VVR with a focus on vasovagal syncope (VVS, temporary loss of consciousness), risk factors, and possible consequences of VVR/VVS for donors, as well as effects of interventions that are used to reduce VVR/VVS among blood donors. We also discuss mechanisms underlying VVS and evolutionary explanations for VVS. Methods: Relevant studies were found by search in PubMed. Results: Reported incidence of VVS varies from 0.1% to 0.5%, with higher incidence among younger and first-time donors, but mixed results have been found for gender differences: whereas some studies report higher incidence among female donors, other studies find no differences. Anxiety, fear of needles or seeing blood are frequent triggers of VVR/VVS, particularly among first-time donors. Donors who have experienced VVR/VVS are less likely to return to donate. Physiologic interventions such as pre-donation water intake and applied muscle tension during donation, alone or in combination, have shown effect in reducing VVR/VVS in several studies. Psychological interventions such as distraction and social support have also shown to reduce the risk of VVR/VVS. From an evolutionary perspective, VVS may have had a survival advantage in the distant past.https://www.bioingenioren.no/fag/fag-oversiktsartikkel/vasovagale-reaksjoner-blant-blodgivere--forekomst-mekanismer-risikofaktore-implikasjoner-og-forebyggende-tiltak---en-litteraturstudie/blood donationvasovagal syncopebaroreceptorfirst-time donor |
| spellingShingle | Sadaf Nabi Bhatti Dorthe Charlotte Johannessen Abid Hussain Llohn Seyed Ali Mousavi Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study Bioingeniøren blood donation vasovagal syncope baroreceptor first-time donor |
| title | Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study |
| title_full | Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study |
| title_fullStr | Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study |
| title_full_unstemmed | Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study |
| title_short | Vasovagal reactions among blood donors - incidence, mechanisms, risk factors, implications and preventive measures - a literature study |
| title_sort | vasovagal reactions among blood donors incidence mechanisms risk factors implications and preventive measures a literature study |
| topic | blood donation vasovagal syncope baroreceptor first-time donor |
| url | https://www.bioingenioren.no/fag/fag-oversiktsartikkel/vasovagale-reaksjoner-blant-blodgivere--forekomst-mekanismer-risikofaktore-implikasjoner-og-forebyggende-tiltak---en-litteraturstudie/ |
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