The role of FLT3 inhibitors as maintenance therapy following hematopoietic stem cell transplant

The role of FLT3 inhibitors as maintenance therapy following hematopoietic stem cell transplant

Activating mutations in FLT3 in acute myeloid leukemia (AML) portend a poor prognosis, and targeting FLT3 with a tyrosine kinase inhibitor has been an area of intense research recently. Most FLT3 mutated AML patients undergo hematopoietic stem cell transplantation (HSCT) as standard of care but a si...

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Bibliographic Details
Main Authors: Grace Xiuqing Li, Lan Wang, Bassam Yaghmour, Giridharan Ramsingh, George Yaghmour
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Leukemia Research Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048918300499

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