Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows
The diet energy level plays a vital role in the energy balance of transition cows. We investigated the effects of high dietary energy density on body metabolism. Twenty multiparous Angus cows were randomly assigned to two treatment groups (10 cows/treatment), one receiving a high-energy (HE) diet (N...
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MDPI AG
2022-04-01
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| Online Access: | https://www.mdpi.com/2076-2615/12/9/1147 |
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| author | Hao Chen Chunjie Wang Simujide Huasai Aorigele Chen |
| author_facet | Hao Chen Chunjie Wang Simujide Huasai Aorigele Chen |
| author_sort | Hao Chen |
| collection | DOAJ |
| description | The diet energy level plays a vital role in the energy balance of transition cows. We investigated the effects of high dietary energy density on body metabolism. Twenty multiparous Angus cows were randomly assigned to two treatment groups (10 cows/treatment), one receiving a high-energy (HE) diet (NEm = 1.67 Mcal/kg of DM) and the other administered a control (CON) diet (NEm = 1.53 Mcal/kg of DM). The results indicated that feeding a high-energy diet resulted in higher plasma glucose concentration and lower concentrations of plasma NEFA and BHBA on d 14 relative to calving in the HE-fed cows compared to the CON-fed ones. The postpartum plasma levels of T-AOC were lower in cows that received the CON diet than in cows in the HE group, while the concentration of malondialdehyde (MDA) showed an opposite trend. Among the 51 significantly different metabolites, the concentrations of most identified fatty acids decreased in HE cows. The concentrations of inosine, glutamine, and citric acid were higher in HE-fed cows than in CON-fed cows. Enrichment analysis revealed that linoleic acid metabolism, valine, leucine as well as isoleucine biosynthesis, and glycerophospholipid metabolism were significantly enriched in the two groups. |
| first_indexed | 2024-03-10T04:24:11Z |
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| id | doaj.art-ba23fc9cafb04675addef96195da72a0 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T04:24:11Z |
| publishDate | 2022-04-01 |
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| spelling | doaj.art-ba23fc9cafb04675addef96195da72a02023-11-23T07:43:01ZengMDPI AGAnimals2076-26152022-04-01129114710.3390/ani12091147Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus CowsHao Chen0Chunjie Wang1Simujide Huasai2Aorigele Chen3College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, ChinaCollege of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, ChinaCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, ChinaThe diet energy level plays a vital role in the energy balance of transition cows. We investigated the effects of high dietary energy density on body metabolism. Twenty multiparous Angus cows were randomly assigned to two treatment groups (10 cows/treatment), one receiving a high-energy (HE) diet (NEm = 1.67 Mcal/kg of DM) and the other administered a control (CON) diet (NEm = 1.53 Mcal/kg of DM). The results indicated that feeding a high-energy diet resulted in higher plasma glucose concentration and lower concentrations of plasma NEFA and BHBA on d 14 relative to calving in the HE-fed cows compared to the CON-fed ones. The postpartum plasma levels of T-AOC were lower in cows that received the CON diet than in cows in the HE group, while the concentration of malondialdehyde (MDA) showed an opposite trend. Among the 51 significantly different metabolites, the concentrations of most identified fatty acids decreased in HE cows. The concentrations of inosine, glutamine, and citric acid were higher in HE-fed cows than in CON-fed cows. Enrichment analysis revealed that linoleic acid metabolism, valine, leucine as well as isoleucine biosynthesis, and glycerophospholipid metabolism were significantly enriched in the two groups.https://www.mdpi.com/2076-2615/12/9/1147cowdietary energy densityplasmanegative energy balancemetabolic profiles |
| spellingShingle | Hao Chen Chunjie Wang Simujide Huasai Aorigele Chen Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows Animals cow dietary energy density plasma negative energy balance metabolic profiles |
| title | Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows |
| title_full | Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows |
| title_fullStr | Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows |
| title_full_unstemmed | Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows |
| title_short | Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows |
| title_sort | metabolomics reveals the effects of high dietary energy density on the metabolism of transition angus cows |
| topic | cow dietary energy density plasma negative energy balance metabolic profiles |
| url | https://www.mdpi.com/2076-2615/12/9/1147 |
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