CRISPR Disruption of <i>BmOvo</i> Resulted in the Failure of Emergence and Affected the Wing and Gonad Development in the Silkworm <i>Bombyx mori</i>

CRISPR Disruption of <i>BmOvo</i> Resulted in the Failure of Emergence and Affected the Wing and Gonad Development in the Silkworm <i>Bombyx mori</i>

The domesticated silkworm is an economically important insect that is widely used as a lepidopteran insect model. Although somatic sex determination in the silkworm is well characterized, germline sex determination is not. Here, we used the transgenic-based CRISPR/Cas9 genome editing system to study...

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Bibliographic Details
Main Authors: Honglun Bi, Xia Xu, Xiaowei Li, Yong Zhang, Yongping Huang, Kai Li, Jun Xu
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Insects
Subjects:
<i>Bombyx mori</i>
CRISPR/Cas9
<i>BmOvo</i>
wing development
gonad development
Online Access:https://www.mdpi.com/2075-4450/10/8/254

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