Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma

Blood viscosity is the defining health indicator for hyperviscosity syndrome patients. This paper introduces an alternative approach for the real-time monitoring of blood viscosity by employing a surface-horizontal surface acoustic wave (SH-SAW) device at room temperature. A novel bi-layer waveguide...

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Main Authors: Kun-Lin Lee, Glen Kowach, Fang Li, Ioana Voiculescu
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/23/13/5911
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author Kun-Lin Lee
Glen Kowach
Fang Li
Ioana Voiculescu
author_facet Kun-Lin Lee
Glen Kowach
Fang Li
Ioana Voiculescu
author_sort Kun-Lin Lee
collection DOAJ
description Blood viscosity is the defining health indicator for hyperviscosity syndrome patients. This paper introduces an alternative approach for the real-time monitoring of blood viscosity by employing a surface-horizontal surface acoustic wave (SH-SAW) device at room temperature. A novel bi-layer waveguide is constructed on top of the SAW device. This device enables the SAW sensing of liquid droplets utilizing a bi-layer waveguide, consisting of a zinc oxide (ZnO) enhancement layer and Parlyene C, that facilitates the promotion of the surface horizontal mode. The ZnO piezoelectric thin-film layer enhanced the local particle displacement and dielectric coupling while the Parylene C layer constrained the wave mode at the interface of the piezoelectric material and polymer material. The device was tested with a liquid drop on the SAW delay-line path. Both experimental and finite element analysis results demonstrated the benefits of the bi-layer waveguide. The simulation results confirmed that the displacement field of local particles increased 9 times from 1.261 nm to 11.353 nm with the Parylene C/ZnO bi-layer waveguide structure. The device demonstrated a sensitivity of 3.57 ± 0.3125 kHz shift per centipoise enabling the potential for high precision blood viscosity monitoring.
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spelling doaj.art-ba2670acfa434379a8f161efc50d3c122023-11-18T17:28:36ZengMDPI AGSensors1424-82202023-06-012313591110.3390/s23135911Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and PlasmaKun-Lin Lee0Glen Kowach1Fang Li2Ioana Voiculescu3Department of Mechanical Engineering, The City College of the City University of New York, New York, NY 10031, USADepartment of Chemistry and Biochemistry, The City College of the City University of New York, New York, NY 10031, USADepartment of Mechanical Engineering, New York Institute of Technology, Old Westbury, NY 11568, USADepartment of Mechanical Engineering, The City College of the City University of New York, New York, NY 10031, USABlood viscosity is the defining health indicator for hyperviscosity syndrome patients. This paper introduces an alternative approach for the real-time monitoring of blood viscosity by employing a surface-horizontal surface acoustic wave (SH-SAW) device at room temperature. A novel bi-layer waveguide is constructed on top of the SAW device. This device enables the SAW sensing of liquid droplets utilizing a bi-layer waveguide, consisting of a zinc oxide (ZnO) enhancement layer and Parlyene C, that facilitates the promotion of the surface horizontal mode. The ZnO piezoelectric thin-film layer enhanced the local particle displacement and dielectric coupling while the Parylene C layer constrained the wave mode at the interface of the piezoelectric material and polymer material. The device was tested with a liquid drop on the SAW delay-line path. Both experimental and finite element analysis results demonstrated the benefits of the bi-layer waveguide. The simulation results confirmed that the displacement field of local particles increased 9 times from 1.261 nm to 11.353 nm with the Parylene C/ZnO bi-layer waveguide structure. The device demonstrated a sensitivity of 3.57 ± 0.3125 kHz shift per centipoise enabling the potential for high precision blood viscosity monitoring.https://www.mdpi.com/1424-8220/23/13/5911surface acoustic wavesSH-SAWquartzZnOwaveguidepiezoelectric thin-film
spellingShingle Kun-Lin Lee
Glen Kowach
Fang Li
Ioana Voiculescu
Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma
Sensors
surface acoustic waves
SH-SAW
quartz
ZnO
waveguide
piezoelectric thin-film
title Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma
title_full Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma
title_fullStr Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma
title_full_unstemmed Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma
title_short Liquid Viscosity Sensor Using a Surface Acoustic Wave Device for Medical Applications Including Blood and Plasma
title_sort liquid viscosity sensor using a surface acoustic wave device for medical applications including blood and plasma
topic surface acoustic waves
SH-SAW
quartz
ZnO
waveguide
piezoelectric thin-film
url https://www.mdpi.com/1424-8220/23/13/5911
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AT glenkowach liquidviscositysensorusingasurfaceacousticwavedeviceformedicalapplicationsincludingbloodandplasma
AT fangli liquidviscositysensorusingasurfaceacousticwavedeviceformedicalapplicationsincludingbloodandplasma
AT ioanavoiculescu liquidviscositysensorusingasurfaceacousticwavedeviceformedicalapplicationsincludingbloodandplasma