The Metabolic Redox Regime of <named-content content-type="genus-species">Pseudomonas putida</named-content> Tunes Its Evolvability toward Novel Xenobiotic Substrates

The Metabolic Redox Regime of <named-content content-type="genus-species">Pseudomonas putida</named-content> Tunes Its Evolvability toward Novel Xenobiotic Substrates

ABSTRACT During evolution of biodegradation pathways for xenobiotic compounds involving Rieske nonheme iron oxygenases, the transition toward novel substrates is frequently associated with faulty reactions. Such events release reactive oxygen species (ROS), which are endowed with high mutagenic pote...

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Bibliographic Details
Main Authors: Özlem Akkaya, Danilo R. Pérez-Pantoja, Belén Calles, Pablo I. Nikel, Víctor de Lorenzo
Format: Article
Language:English
Published: American Society for Microbiology 2018-09-01
Series:mBio
Subjects:
NADPH oxidases
Pseudomonas putida
reactive oxygen species
biodegradation
dinitrotoluene
evolution
Online Access:https://journals.asm.org/doi/10.1128/mBio.01512-18

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