eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.

eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.

Antibody-dependent cell-mediated cytotoxity (ADCC) can eliminate HIV-1 infected cells, and may help reduce the reservoir of latent virus in infected patients. Sera of HIV-1 positive individuals include a number of antibodies that recognize epitopes usually occluded on HIV-1 envelope glycoprotein (En...

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Bibliographic Details
Main Authors: Meredith E Davis-Gardner, Matthew R Gardner, Barnett Alfant, Michael Farzan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5749896?pdf=render

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